The present invention provides a method of reducing the concentration of an iodide compound using an ion exchange resin. The ion exchange resin is a macroporous resin having sulfur functional groups exchanged with silver, a dry weight capacity of at least 5.0 eq/kg, a mean pore diameter (D.sub.50) of about 400-800 .ANG., a pore volume of about 0.4-0.6 ml/g, and a surface area of about 20-40 m.sup.2/g.