The compositions of the present invention relate to improved shampoo compositions having from about from about 5 to about 50 weight percent of a detersive surfactant, at least about 0.05 weight percent of a cationic polymer least about 0.05 weight percent of a cationic guar derivative having a molecular weight from about 10,000 to about 10,000,000 and a charge density from about 1.25 meq/g to about 7 meq/g, and at least about 20.0 weight percent of an aqueous carrier.

Compositions for cleansing are disclosed that are not irritating to human skin. A composition is disclosed that includes at least 2% of a mixture of a salt of an alkyl sulfoacetate and a salt of an ethoxylated alkyl sulfosuccinate, at least 3% of a salt of an ethoxylated alkyl sulfate, at least 1% of an amphoteric surfactant, at least 0.05% of an alkyl glucoside, and at least 0.005% of a phospholipid. A composition for cleansing is disclosed that includes about 2% to 70% of a mixture of a salt of an alkyl sulfoacetate and a salt of an ethoxylated alkyl sulfosuccinate, about 3% to 40% of a salt of an ethoxylated alkyl sulfate, about 1% to 40% of an amphoteric surfactant, about 0.05% to 10% of an alkyl glucoside, and about 0.005% to 10% of a phospholipid. A cleansing composition is further disclosed that includes about 41% of a mixture of alkyl sulfoacetate and ethoxylated alkyl sulfosuccinate, about 34% of an ethoxylated alkyl sulfate, about 22% of an amphoteric surfactant, about 2% of a alkyl glucoside, and about 0.5% of a phospholipid. A composition for cleansing is also described which includes about 2% to 50% of a mixture of a salt of a sodium lauryl sulfoacetate and Disodium Laureth Sulfosuccinate, about 3% to 35% of Ammonium Laureth Sulfate, about 1% to 30% of Cocamidopropyl Betaine, about 0.05% to 8% of Coco-Glucoside and Coconut Oil, and about 0.005% to 5% of a phospholipid. A method of cleaning is also described, which includes contacting a surface to be cleansed with the composition of the invention. The composition can be used in a variety of personal care or household cleansers, such as contact lens care products, shampoos, soaps, body washes, mouthwashes, toothpastes, oral rinses, facial and wound cleansers, eye makeup removers, laundry and dishwashing detergents, and others.

Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.

Disclosed are conditioning shampoo compositions which provide improved hair or skin conditioning performance. These compositions comprise a detersive surfactant, select ethoxylated fatty alcohols having a fatty alcohol moiety containing from about 6 to about 30 carbon atoms and an ethoxylate chain containing from about 5 to about 150 moles of ethoxylation, a nonvolatile conditioning agent, preferably a nonvolatile silicone conditioning agent, having an average particle size of from about 5 um to about 2000 um, and water. The select ethoxylated fatty alcohols provide improved hair or skin conditioning by improving silicone deposition of large particle conditioning agents onto the hair or skin.

Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.