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Transdermal delivery of calcium channel blockers, such as nifedipine



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Patent 6106856
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Document Number
US Patent 6106856
Issued Date
August 22, 2000
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Abstract
A transdermal formulation of dihydropyridine calcium antagonists and specifically nifedipine, nimodipine and nitrendipine. The calcium antagonists are dispersed in a mixed liquid. The mixed liquid comprises varying mole fractions of cis-oleic acid and dimethylisosorbide dispersed in a polypropylene glycol base.
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Number of Claims:
14
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Published
August 22, 2000
Application Number
08/398,664
Filed
March 3, 1995
US Classification
424/448   424/449 514/946
Int'l Classification
B60J   7/08   (20060101)  
Parent Case
This application is a continuation-in-part of Ser. No. 08/203,430 filed Mar. 1, 1994, now abandoned.
USPTO Field of Search
429/448   429/449   514/946  
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