The present invention relates to a circular disk, comprising two material layers that are joined together, wherein said disk contains microfluidic structures formed of a channel and/or cavity system defined between the two material layers, the recesses which correspond to the channels and/or cavities, respectively, being formed in one or both of opposed layer surfaces.
This application is a divisional of application Ser. No. 08/564,217, filed on Dec. 15, 1995, U.S. Pat. No. 6,126,765 application Ser. No. 08/564,217 is the national phase of phase of PCT International Application No. PCT/SE94/00584 filed on Jun. 14, 1994 under 35 U.S.C. .sctn.371. The entire contents of each of the above-identified applications are hereby incorporated by reference.
A method for rendering a surface covered by a plastic material more hydrophilic by treatment with a gas plasma non-polymerizable gas. The method is characterized in that the intensity of the plasma is selected so that the surface becomes permanently more hydrophilic. Also disclosed is a naked plasma treated surface of plastic having an immediate water contact angle of .ltoreq.30.degree., said water contact angle is changed .+-.20 and/or less than 5% upon washing with an ethanol/water mixture (70% w/w).
A microfluidic disc having one or more enclosed microchannel structures, and the microchannel structures are intended to be used for transport of transporting liquids. The device is characterized in that at least a part of the inner walls of each of one or more microchannel structures are treated with a gas plasma having one or more organic precursor compounds.
A method of controlled heating of a micro channel reactor structure (46, 48, 50) comprises providing a structure (b1, b2, B1, B2) defining a desired temperature profile. A preferred embodiment of a heating element structure comprises a pattern of areas of a material capable of providing heat when energized, disposed over said micro channel reactor structure.
The present invention concerns a method and an arrangement for reducing noise in a substance raw data image containing noise. The method may comprise following steps in any order for removing different noise signals contributions step-by-step in any order in a substance raw data image: reducing background radiation; reducing peak disturbance; locating the detection area within the search area; moving binary artifacts; removing unwanted areas of the detection area; and applying default detection area in noisy images). The present invention also relates to a method and an arrangement for determining a measure of at least one substance.
A detector arrangement, which comprises a rotatable microfluidic disc and a spectrophotometric detector unit. The arrangement is characterized in that the detector unit is based on surface plasmon resonance (SPR) and is capable of measuring an analyte within the detection microcavities, each of which is part of a microchannel structure.A microfluidic disc having an axis of symmetry and comprising microchannel structures, each of which has an upstream functional part that is at a shorter radial position than a downstream functional part. The disc is characterized in that there are detection microcavities (DMCs) in at least a part of said microchannel structures, and that each of said DMCs has an SPR surface on an inner wall and a detection detection window extending from the SPR surface to the surface of the disc.The use of the detector arrangement and microfluidic disc described above for determining: a) if the content in one or more of the DMCs is a liquid or a solid state or a gas, and/or b) a feature of an analyte that may be present in a liquid which is present in one or more of the DMCs.
