May 3, 2005

The invention relates to methods and materials for use in the typing, diagnosis, prevention and/or treatment of prion disease.

17

May 3, 2005

09/958,517

February 12, 2002

435/23   435/184 435/212 435/219 435/4 530/350 530/400

C07K   14/435   (20060101)   G01N   33/569   (20060101)   G01N   33/68   (20060101)   C07K   14/47   (20060101)  

The present application is a continuation of co-pending PCT International Application No. PCT/GB00/01327, having an International filing date of Apr. 7, 2000 and a priority date of Apr. 9, 1999 and entitled "METHOD TO TYPE PRION PROTEINS".

Apr 09, 1999 [GB] 9908059

435/5   435/7.1   435/7.5   435/7.9   435/23   435/7.92   435/68.1   435/69.1   435/4   435/183   435/184   435/212   435/219   424/183   424/184   424/185.1   424/212   424/219   424/405   422/28   530/328   530/350   530/400   530/403   436/501  

7566530 - Method for detecting PrP using at least one positive charge and/or at least one glycosidic bond and a ligand other than a protein ligand - Owned by Biomerieux (Marcy l'Etoile,FR) Universite Claude Bernard Lyon (Villeubanne,FR) Centre National de la Recherche Scientifique (Paris,FR) Agence Francaise de Securite Sanit Aire des Aliments (Maisons-Alfort,FR) The invention relates to a method for detecting PrP in a biological human or animal sample that may contain PrP. The inventive method is characterised in that it uses a molecule containing at least one positive charge and/or at least one osidic bond and a ligand other than a proteinic ligand selected from macrocyclic ligands and glycosaminoglycanes.