A PET system includes an improved image reconstruction algorithm based on an improved modeling of the point-spread function. PET time of flight data is used to obtain a mean emitting point and a time of flight probability function. This information is then used to model the point-spread function. The time of flight probability function and the detector response function are used to define a probability volume for a given line of response, which is then used in the reconstruction of the image.
CROSS REFERENCE TO RELATED APPLICATIONS
This application claims the benefit of U.S. provisional application Ser. No. 60/595,930 filed Aug. 18, 2005, which is incorporated herein by reference.