US Patent 7384760 - Methods for assaying inhibitors of S-adenosylhomocysteine (SAH) hydrolase and S-adenosylmethionine (SAM)-dependent methyltransferase

Methods for assaying inhibitors of S-adenosylhomocysteine (SAH) hydrolase and S-adenosylmethionine (SAM)-dependent methyltransferase

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Document Number

US Patent 7384760

Issued Date

June 10, 2008

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Inventors

Yuan; Chong-Sheng (San Diego, CA)

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Ye; Qi-Zhuang (San Diego, CA)

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Xie; Sheng-Xue (Lawrence, KS)

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Abstract

The present invention relates to methods for assaying inhibitors for S-adenosylhomocysteine (SAH) hydrolases and assaying inhibitors for S-adenosylmethionine (SAM)-dependent methyltransferases. The methods are amenable for use in high throughput formats. Kits for performing the methods are also provided.