Process for the synthesis of compounds of formula (I): ##STR00001## wherein R.sub.1 and R.sub.2, which may be the same or different, each represent a linear or branched (C.sub.1 C.sub.8)alkoxy group or form, together with the carbon atom carrying them, a 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring.Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.

The present invention relates to a process for preparing TEDA solutions comprising a solvent selected from the group consisting of polyhydric alcohols and ethers of polyhydric alcohols. The process comprises passing gaseous TEDA into the solvent and subsequently treating the solutions with one or more suitable adsorbents. This gives solutions which have only low color numbers and are color-stable on storage. The solutions can be used as such in preferred applications of TEDA, preferably polyuret...

In a process for the purification of triethylenediamine (TEDA) in which TEDA is vaporized and the gaseous TEDA is passed into a liquid solvent and is subsequently crystallized from this, the mother liquor obtained after the TEDA has been crystallized is extracted with an extractant which is immiscible or only slightly miscible with the solvent of the mother liquor and in which TEDA is readily soluble, and the TEDA-depleted mother liquor obtained after extraction and/or the TEDA-enriched extracta...

A subject-matter of the present invention is a novel process for the synthesis of hexanitrohexaazaisowurtzitane (HNIW), a compound of use as energetic filler in powders, propellants and explosives.This process comprises a first stage of reaction of an .alpha.,.beta.-dicarbonyl derivative with a primary amine which makes it possible to form a hexasubstituted hexaazaisowurtzitane derivative.The HNIW is subsequently obtained directly, in a single reaction stage, by nitration of the hexasubstituted ...

Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein ##STR00001##

Highly pure triethylenediamine is obtained by a process in which triethylenediamine is freed from high boilers and then the triethylenediamine is vaporized from the mixture thus obtained and is passed into a liquid solvent. The process makes it possible in particular to obtain highly pure solutions of triethylenediamine. Crystallization is generally unnecessary.

Process for purifying triethylenediamine (TEDA) by disillation, in which the fractionation is carried out in a dividing wall column.

A process for producing compound 1,4,7,10,13,16,21,24-octaazabicyclo[8.8.8]hexacosa, 4,6,13,15,21,23-hexaene (2) and then compound 1,4,7,10,13,16,21,24-octaazabicyclo[8.8.8]hexacosane (1) from compound (2) is described. The process uses a reaction between triaminoethylamine and glyoxal in the presence of water, alcohol and tertiary amine at low temperature to produce compound 2. Then compound 1 is produced from compound 2 by reduction with an alkali metal containing ammonia as the reductant. The...

The method of manufacture, method of use and fungicidal active compounds are described herein. The active compounds have the following formula: ##SPC1## Wherein R can be selected from the group consisting of hydrogen, sodium, potassium and ammonium.

Compositions of a pharmaceutically acceptable carrier and a 3-nitroimidazo[1,2-b]pyridazine and methods of using the same are described. These compositions are useful for their anti-protozoal activity as anti-trichomonal and anti-amebic agents.