A method for analyzing a substance, comprising: a step of obtaining a dispersion complex by co-existing fine particles having a dispersion property higher than that of lyophobic fine particles in a dispersion phase of the lyophobic fine particles at a concentration sufficient for covering a periphery of a lyophobic fine particle group; a step of contacting the dispersion complex and a fluid containing an analyte; and a step of analyzing the analyte using an optical measuring means, wherein the l...

Immunochemical composites consisting of saturating amounts of radio-labelled triiodothyronine (T.sub.3) or thyroxine (T.sub.4) complexed respectively to anti-T.sub.3 or anti-T.sub.4 antisera covalently coupled to suspendable porous glass particles via an intermediate silane coupling agent. The composites are pre-loaded into individual tubes used in solid phase radioimmunoassay of T.sub.3 or T.sub.4, requiring the addition of only test serum or standard, thereby minimizing chances of erroneous as...

Improved heterogeneous fluorescence assays are provided which employ solid supports comprising controlled pore glass particles which are substantially transparent at both the wavelength used to excite the fluorescent probe used in the assay and at the emission wavelength of the probe. The assays achieve sensitivities comparable to those achieved with radioimmunoassays without the need to concentrate the particles prior to the fluorescent measurement as in prior art heterogeneous fluorescence ass...

Clinically significant concentrations of digoxin can be determined by reacting an unknown amount of digoxin, a known amount of labelled digoxin, and a composite consisting of anti-digoxin antibodies coupled through an intermediate silane to magnetically responsive particles; magnetically separating the immunochemical complexes formed thereby, counting the radioactivity of either the separated products or remaining solution, and relating the count to a standard curve.

A land mobile radio communication system has a plurality of cell sites, each of which typically has a plurality of repeaters. The over-the-air radio communications between the cell site repeaters and the mobile radios in the system include both a voice component and a data component. The data component is carried as low-frequency subaudible information. Communication channels are provided between the radio users at each site as well as between users at different sites and between mobile radio us...

Reagent and method for detecting the presence of hepatitis associated antigen (HAA) in blood serum. The reagent comprises anti-HAA antibodies coupled via an intermediate silane to a plurality of siliceous particles having a surface area of at least about 1 m.sup.2 /g and, if the particles are porous, an average pore diameter of at least about 1000 A. The test method comprises the steps of incubating a serum sample with the reagent to complex any HAA in the samplewith the antibodies of the reagen...

Bifunctional immunoadsorbents containing complementary antigens and antibodies which are useful for detecting the presence of complementary antigens and antibodies in serum are described.

Estrogen receptor protein, estrophilin, in a tissue sample is detected and quantified by radiochemical methods involving selective binding of the protein to controlled pore glass beads. Also disclosed are methods for selectively removing undesirable degradation products from radiochemically labelled non-polar steroid reagents, especially estradiol.

A method for detecting the end point in immunochemical and serodiagnostic tests involving agglutination is described wherein the test is carried out on a curved slide having a curvature sufficient to produce a discernible pattern at the end point.

Silica-coated nanoparticles functionalized with biologically active molecules such as antibodies and nucleotides are used to label cells, to detect and isolate nucleic acid molecules having specific nucleotide sequences, and to separate a mixture of different nucleic acid molecules.