Compounds containing and method employing, as the essential ingredient, novel substituted xanthone carboxylic acid compound which are useful in the treatment of allergic conditions. Method for preparing these compounds and compositions and intermediates therein are also disclosed. 7-Trifluoromethylxanthone-2-carboxylic acid is illustrated as representative of the class.

Fungus diseases of plants are combated by applying to foliage or to the soil in the vicinity of the plants 1,8-naphthalic anhydride as a dust or a foliar spray. The method is particularly effective against apple scab and late blight and leaves no accummulation of inorganic residues as a result of repeated use.

Compositions containing and methods employing, as the essential ingredient, novel substituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 6-Acetylxanthone-2-carboxylic acid is illustrated as a representative compound.

Methods employing as the essential ingredient, novel substituted xanthone carboxylic acid compounds in the treatment of the symptons of the asthmatic condition resulting from an antigen-antibody reaction. Methods for preparing these compounds and compositions and intermediates therein are also disclosed - 7 - (methylthio) - xanthone - 2 - carbonylic acid is illustrated as representative of the class.

Novel polycyclic gamma-pyrone derivatives having a carboxaldehyde group on the 3-position and optionally substituted on the 5, 6, 7, 8, 9 or 10 positions with a hydroxy, lower alkyl or lower alkoxy group are disclosed, as well as the corresponding N-substituted, formyl imine derivatives thereof. These compounds, and pharmaceutical compositions containing these compounds, are useful for the treatment of allergic conditions and for the treatment of hyperacidity.

A method of anabolic treatment in humans comprises administering a compound of the following formula: ##SPC1## Wherein R is halosubstituted, nitrosubstituted, or unsubstituted benzyl, R.sup.2 is hydrogen, methyl or carboxy, and R.sup.3 and R.sup.4 are hydrogen, methoxy or nitro. Pharmaceutical compositions are also disclosed.

Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methylthio-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di-(methylthio)xanthone-2-carboxylic acid are illustrated as representative compounds.

An agent for inhibiting the binding of 5.alpha.-dihydrotestosterone with androgen receptor, which comprises at least one extract from herbs or one of specific xanthone compounds, and a process for obtaining the agent.

There is described a method of treatment of certain psychiatric conditions which method comprises administration of a compound of the formula I, ##STR1## or a therapeutically acceptacle salt, ester or amide thereof, (as active ingredient), to a patient having such a condition.

Antibiotic A-28086 complex, comprising microbiologically active, structurally related factors A, B, and D, produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 5758. Individual factors A, B, and D are separated and isolated by chromatography. The A-28086 antibiotics are antibacterial, antifungal, antiviral, anti-PPLO, anticoccidial, insecticidal and acaricidal agents and also increase feed-utilization efficiency in ruminants.