Thiolpulvinic acid derivatives having anti-arthritic activity prepared by treating the corresponding pulvinic acid dilactone with an active derivative of the appropriate mercaptan.

The present invention concerns the use of the compounds of the formula: ##EQU1## wherein R.sub.1 to R.sub.9 have various significances including e.g. alkyl, X and Y include O and S, and s, v, w and z are O or whole numbers and Ar.sub.1 is substituted phenyl, as insecticides, and insecticidal compositions containing said compounds as active agent.

Method of destroying mosquito larvae by applying to them the compound 3,4-methylenedioxy-cinnamyloxybenzene.

The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. ##STR1##

There are disclosed pharmaceutical preparations and methods for the use thereof which have a cardioprotective action useful in coronary insufficiency, in the prevention of the constitution of an infarction or of sudden death. It consists in the utilization of amiodarone, a nitrate derivative and a beta-blocker.

A treatment for senile dementia of the Alzheimer's type comprising administering to the patient a tertiary amine of the formula ##STR1## wherein R.sup.1 is alkyl, alkoxy, alkylthio or dialkylamino hydroxyl, hydrogen, chlorine or fluorine; R.sup.2 is hydrogen, or when R.sup.1 is hydrogen, alkyl, alkoxy, alkylthio, alkylthioamino, hydroxyl, chlorine or fluorine; R.sup.3 is 1 to 2 carbon alkyl; R.sup.4 is 1 to 3 carbon alkyl; R.sup.5 is an optionally branched 3 to 12 carbon alkylene; X is oxygen or...

A method of treating skin disorders comprises the step of applying thereto a composition wherein the main active ingredient comprises dimethyl isosorbide. It has been found that dimethyl isosorbide has a dermal penetrating action which can effectively carry it to the source of a skin disorder and that it has antifungal, antiviral and antibacterial effects which make it effective in the treatment of a wide range of skin disorders.

6-Hydroxy-2-(2-hydroxy-4-methoxyphenyl)benzofuran derivatives and related pharmaceutical compositions and methods of treatment are disclosed. The compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, they are useful therapuetic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.

Medicaments containing bilobalid which can be used to control nervous diseases are described.

A stable liquid formulation of the pesticide bendiocarb, especially for ultra low volume application, comprises the bendiocarb suspended in a chemically inert oil of low volatility and of low solubility for bendiocarb.