Novel antifungal and antibacterial agents having a short-kill time comprising dimethyl sulfoxide, ethanol or isopropanol and an effective amount of at least one diester of 2,2,4-trimethylpentanediol-1,3 and aliphatic carboxylic acids of two to 12 carbon atoms. 13 Claims, No Drawings

A composition is disclosed which is suitable for the prevention and treatment of kidney dysfunctions and diseases and which can therefore take the form of a food supplement or of an actual medicinal drug, comprising a combination of acetyl L-carnitine and propionyl L-carnitine or their pharmacologically acceptable salts.

Methods of using propionoyloxymethyl propionate ("POMP") and butyroyloxymethyl butyrate ("BOMB") are disclosed. Methods of treating cancer using these compounds are disclosed. The compounds are effective in the inhibition of histone deacetylase.

The present invention provides a method and composition for treating pruritus, and also psoriasis which includes applying a compound of formula (I) in a suitable formulation to the affected area. Compounds of formula (I) can also be formulated as a vaginal cream to inhibit viruses such as HIV, and possibly prevent the transmission of other sexually transmitted diseases.

The use of an alkanoyl-L-carnitine, e.g., acetyl-L-carnitine, or a pharmacologically acceptable salt thereof is disclosed to produce a medicament for the therapeutic treatment or prophylaxis of glutamate-mediated cytological disturbances or diseases.

A process for using glycolic acid derivatives to control antimicrobial activity is disclosed. The process comprises: Contacting a microbe with an antimicrobial composition containing, as its active ingredient, a member selected from the group consisting of N,N-bis(pelargonoyloxyethyl)pelargonoyloxyacetamide, N,N-bis(lauroyloxyethyl)lauroyloxyacetamide, N,N-bis (oleoyloxyethyl)oleoyloxyacetamide, N,N-bis(trimethylacetyloxyethyl)trimethylacetylacetamide, carboethoxymethyl hydrocinnamate, and bis(c...

A pharmaceutical composition administerable either orally or parenterally, comprising a therapeutically effective amount of an acyl-carnitine, or a pharmaceutically acceptable salt, ester or amide thereof, wherein the acyl radical is selected from the group formed by acetyl, propionyl, butyryl, hydroxybutyryl and acetoacetyl is useful in the therapeutical treatment of patients with impaired cerebral metabolism, as for instance in the states of senile and presenile psychomotor involution and in s...

Based on the discovery that carnitine and some lower acyl-carnitines act on the phospholipids in the wall of erythrocytes restoring the elasticity of the erythrocytic membrane, a new therapeutic use of the compounds mentioned above in the treatment of the pathology of the veins, typically venous stasis, is disclosed.

Esters of acyl L-carnitine with gamma-hydroxybutyric acid, both as pharmacologically acceptable salts of formula (1) ##STR1## and as inner salts of formula (1') ##STR2## wherein X.sup.- is the anion of a pharmacologically acceptable acid and R is a straight or branched acyl group having from 2 to 5 carbon atoms, are used for producing pharmaceutical compositions effective for treating hepatopathies.

3-methylthiopropionyl L-carnitine and its pharmacologically acceptable salts are active on the cardiovascular system, particularly in the treatment of myocardial anoxia, cardiac ischaemia, arrhythmias and congestive heart failure.