HCA Supplementation improves wound healing and immunomodulation/immunoregulation, including improving depressed immune function and also reducing excessive immune activity such as is found in elevated humoral immunity linked to allergies and autoimmune diseases. The benefits of HCA are especially pronounced with the use of the preferred salt of the acid, potassium hydroxycitrate, and may be further potentiated by the use of a controlled-release form of the compound.

(-)-Hydroxycitrate (HCA) supplementation constitutes a novel means of reducing the loss in bone mineral content such as that usually found in osteoporosis and the related loss in bone quality (protection against the corticoid-induced loss in non-mineral bone components). Similarly, HCA supplementation constitutes a novel means of reducing stress-induced bone loss and of reducing other forms of bone loss induced by glucocorticoid-related mechanisms. The discovery that HCA has bone loss-moderating...

Compounds and pharmaceutical compositions for use in the treatment and/or prophylaxis of cartilage and/or bone conditions and for methods of treating such condition. The compounds are salts of strontium that have a water-solubility of from about 1 g/l to about 100 g/l at room temperature, especially amino acid salts of strontium or dicarboxylic acid salts of strontium. Examples of novel water-soluble strontium salts are e.g. strontium glutamate and strontium alpha-ketoglutarate. The present inve...

The present invention provides a formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation. More specifically, the present invention provides a method for administering a formula including glucaric acid or a pharmaceutically acceptable salt thereof for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation in humans and animals. It has been determined that glucaric acid and pharmaceutically acceptable salts thereof s...

The invention provides a method for the treatment of a condition, disorder or a disease of the skin by administering a pharmaceutically acceptable oxalate. Preferably, the oxalate is a transition metal oxalate and the pharmaceutically acceptable carrier is an ointment.

The present invention describes trisodium citrate-containing dialysates and production thereof. Also described are the applications of such dialysates as regional anticoagulants during hemodialysis and all modes of continuous renal replacement therapy which utilize any form of dialysis.

The invention relates to methods of treating insulin resistance in mammals, preferably in humans, which methods comprise administering to a mammal in need thereof an effective amounts of succinic acid or a pharmaceutically acceptable salts thereof.

A method for supplementing dietary potassium, magnesium and citrate is disclosed that comprises orally administering an effective amount of potassium magnesium citrate in a single salt. Methods for decreasing urinary calcium and oxalate by the administration of potassium magnesium citrate in a single salt are also disclosed.

A method for transferring a chelating agent across a cellular membrane by encapsulating the charged chelating agent within liposomes and carrying the liposome-encapsulated chelating agent to the cellular membrane where the liposomes containing the chelating agent will be taken up by the cells, thereby transferring the chelating agent across the cellular membrane. A chelating agent can be introduced into the interior of a cell of a living organism wherein the liposomes will be decomposed, releasi...

A method whereby the glucose metabolism in an individual showing evidence of dysregulation, as is found in insulin resistance, reactive hyperglycemia and/or elevated blood sugar levels and/or diabetes, is improved when that person receives an appropriate oral administration of (-)-hydroxycitric acid. The potassium salt of (-)-hydroxycitric acid is the preferred form of the compound, followed by the sodium salt. The regulation of glucose levels over any given period of time may be improved with a...