This disclosure relates to halo-substituted diphenoxyacetic acid amides and to the use of such compounds as hypolipidemics, e.g., the novel compound bis)p-iodophenoxy) acetic acid amide and the known compound bis(p-chlorophenoxy) acetic acid amide.

Certain 2-phenyl-2-(1-naphthyl)acetamides, having cardiovascular properties and being useful chemical intermediates are prepared through treatment of a 1-phenyl-2-oxo-1,2-dihydronaptho[2,1-b]furan or a 2-phenyl-2-(2-alkoxy-1-naphthyl)acetyl chloride with ammonia or a primary or secondary amine. A typical embodiment is N-t-butyl 2-phenyl-2-(2-hydroxy-1-naphthyl)acetamide. 23 Claims, No Drawings

Apparatus and method for analyzing and encoding graphical data into a serial character stream for transmission over a communications system to a remote data terminal where the character stream is decoded to generate a high resolution graphical display of the data. The graphical display is generated on a teletypewriter which has been modified to permit relatively small, positive and negative incremental movements of the typewriter type carriage and platen in their respective horizontal and vertic...

This invention relates to a method of protecting plants, plant parts or soil from fungus attack by utilization of an effective amount of a 1-(alkoxyaroyl)guanidine having the formula: ##STR1## wherein R contains from 7 to 30 carbon atoms and is alkoxyphenyl, alkenyloxyphenyl or alkoxynaphthyl, which radicals are optionally substituted, in either the aliphatic or the aromatic moiety, with a member of the group of halogen, hydroxy and alkyl of from 1 to 2 carbon atoms; and R' is hydrogen, alkyl of...

The present invention provides pharmaceutical compositions of salicylanilide inhibitors of transcription factor NF-.kappa.B, and methods for treating diseases in which activation of NF-.kappa.B is implicated. More specifically, the present invention provides methods of treatment of a variety of diseases associated with NF-.kappa.B activation including inflammatory disorders; particularly rheumatoid arthritis, inflammatory bowel disease, and asthma; dermatosis, including psoriasis and atopic derm...

The invention features methods for increasing cell death. The invention also features compounds used to increase cell death. The invention further features methods for identifying compounds that increase cell death.

Simultaneously acting depressants to the central nervous system and the cardiovascular system of the formula ##SPC1## Wherein R is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, and halogen radicals; and wherein x is a whole number from 1 to 3.

Methods for the treatment of physiological disorders, including protozoal infections in mammalian and avian species and gastrointestinal and cardiovascular disorders in mammalian species by administering a class of aralkyl- and aralkenyl-acyl, and thioacyl, guanidine compounds, pharmaceutical compositions containing such compounds for systemic administration, and a class of novel aralkenyl-, aryl-substituted cycloalkyl-, and arylsubstituted heterocycle-acyl and thioacyl guanidines.

Disclosed herein are a derivative of dihydroxybenzamide represented by the formula(I): ##STR1## wherein (1) R.sup.1 represents a hydrogen atom or a lower alkyl group and R.sup.2 represents a straight chain-alkyl group of 4 to 12 carbon atoms, a branched chain-alkyl group of 4 to 12 carbon atoms, a cyclo-alkyl group of 4 to 12 carbon atoms, ##STR2## wherein n is an integer of 1 to 6, or a pyridyl group which is substituted or unsubstituted, or (2) R.sup.1 and R.sup.2 are cyclized to make a hetero...

New and useful phenylalkylcarbohydroxamic acids are disclosed of the formula ##STR1## wherein: (a) R is selected from the group consisting of alkoxy of one to six carbon atoms, alkenyloxy of two to six carbon atoms, alkyl of one to six carbon atoms, and benzyloxy; (b) R.sub.1 and R.sub.2 are each selected from the group consisting of hydrogen, alkoxy of one to six carbon atoms, alkenyloxy of two to six carbon atoms, alkyl from one to six carbon atoms, and benzyloxy; (c) R.sub.3 and R.sub.4 are s...