Cholagogic composition containing as active ingredients compounds of the formula: ##SPC1## Wherein R is a hydrogen atom or a lower alkyl group and n is an integer of 1 to 3, and a pharmaceutical carrier therefor.

Pharmacologically active catechol derivatives of formula I ##STR1## wherein R.sub.1 and R.sub.2 independently comprise hydrogen, alkyl, acyl, optionally substituted aroyl, lower alkylsulfonyl or alkylcabamoyl or taken together form a lower alkylidene or cycloalkylidene, X comprises an electronegative substituent such as halogen, nitro, cyano, lower alkylsulfonyl, sulfonamido, aldehyde, caboxyl or trifluoromethyl and R.sub.3 comprises hydrogen, halogen, hydroxy alkyl, amino, nitro, cyano, trifluo...

[n]-paradols (n stands for 6, 7 or 8) are useful and powerful analgesics.

The present invention relates to methods of using and pharmaceutical compositions containing compounds of Formula I: ##STR1## wherein R.sup.1 is hydrogen, --COR.sup.4 wherein R.sup.4 is C.sub.1 -C.sub.4 alkyl, or --COOR.sup.5 wherein R.sup.5 is C.sub.1 -C.sub.4 alkyl; R.sup.2 is C.sub.1 -C.sub.4 alkyl, phenyl, or --OR.sup.6 wherein R.sup.6 is C.sub.1 -C.sub.4 alkyl; and R.sup.3 is C.sub.6 -C.sub.8 alkyl, halogen, or NO.sub.2 ; with the proviso that when R.sup.1 is hydrogen, R.sup.2 is C.sub.1 -C...

Compounds of the formula where R.sub.1 is ethyl or phenyl and R.sub.2 is lower alkyl are useful as fungicides. The compound 3-heptyn-5-one is particularly valuable since it is not toxic to plants.

A pharmaceutical composition comprising idebenone of the present invention is useful for prevention of the progression of dementia.

Use of topical formulations having a content of one or more compounds from the group consisting of ubiquinones and derivatives thereof for treatment of senile xerosis and/or exogenous ageing of the skin.

A compound of the formula: ##STR1## wherein R.sup.1 represents a lower alkyl; R.sup.2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R.sup.3 and R.sup.4 each represents an optionally substituted lower alkyl or a lower alkoxy, or R.sup.3 and R.sup.4 form, taken together, an optionally substituted butadienylene; and X.sup.1 and X.sup.2 each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytot...

A vehicle suspension unit which comprises a telescopic hydraulic damper and a coil compression spring fitting over the body of the damper and abutting at one end against a collar on the piston rod of the damper and at the other end against a sleeve adjustably surrounding the body, the sleeve engaging the body through the intermediary of cam means such that angular movement of the sleeve around the body causes adjustment of the axial position of the sleeve on the body, the cam means positively lo...

This invention is a novel treatment for sexual dysfunctions by administering to a subject exhibiting a sexual dysfunction compounds that upmodulate the AMPA receptor. Methods and compositions for treating sexual dysfunction are provided. Kits containing the compositions in appropriate form for administration are also provided.