1,4-, 1,8- AND 2,5-Dihydroxyanthraquinones are useful for protecting plants from attack by various fungal pathogens when formulated with agricultural additaments.

The invention concerns the use of bis-anthracene compounds isolated from Karwinskia humboldtiana in therapy. The compounds of the invention are selective with a high margin of safety relative to malignant tumor cells and therefore are suitable in particular in the treatment of liver, lung and colon carcinomas and further in the treatment of viral diseases.

Pharmaceutical or cosmetic composition containing as the active component 1,8-dihydroxy-10-phenyl-9-anthrone, and a process for preparing said active component.

The invention relates to the use of anti-cancer drug of a natural compound of vegetal origin, known as aloe-emodin (AE). Indeed, said compound has proved to have a specific biological activity of inhibition on the growth of neuroectodermal tumors, without evident toxic effects. The compound, according to the present invention, has also proved to be cell-specific and it does not show any inhibition on the growth of other cell types such as, for instance, fibroblasts. This pharmacological profile,...

An agent for regulating the motional function of the gastrointestinal tract, which contains as an active ingredient a 41-metyl-4,4a,9,10-tetrahydro-2(3H)-phenanthrenone derivative represented by the following formula I; ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group or an alkoxy group and R.sup.2 represents a hydrogen atom or an alkyl group.

The invention provides therapeutic and biological uses of chemokine-receptor-binding compounds including uses in the treatment of disease states mediated by chemokines. The relevant chemokines may for example be monocyte chemoattractant protein-one (MCP-1) or interleukin-8 (IL-8), and the relevant chemokine receptors may for example be corresponding chemokine receptors (CCR-2, CCR-4, CXCR-1, and CXCR-2). In one aspect, the invention provides for the use of phenanthrene-9,10-dione in the treatmen...

A method of inhibiting thrombus formation in a mammalian subject. The method involves administering to the subject a therapeutically effective dose of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachments to the ring, with polar substituents having terminal sulfonate groups, including esters and amides which are cleavable in vivo.

A psoriasis treatment composition derived from the plant Asphodelus Microcarpus includes 3-methylanthralin, chrysophanol, aloe-emodin, aloe-emodin monoacetate, and/or derivatives thereof. The composition is prepared by extracting a liquid from the Asphodelus Microcarpus root and mixing the liquid with acetic acid. A method of treatment includes applying the composition to an affected area of skin at a frequency sufficient to effect an alleviation of symptoms, typically once per day for 14-56 day...

This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inducing regression and/or palliation of cancer diseases in mammals.

Hypericin, helianthrone and derivatives thereof of general formula (I) ##STR1## wherein the dotted line between positions 11 and 12 represent an optional C11-C12 bond; R is independently selected from the group consisting of hydroxy, C.sub.1 -C.sub.10 alkoxy, NH--C.sub.1 -C.sub.10 alkyl, and NH-hydroxy(C.sub.1 -C.sub.10)alkyl; R' is independently selected from the group consisting of hydroxy and C.sub.1 -C.sub.10 alkoxy; R" is independently selected from the group consisting of hydrogen, hydroxy...