Novel N-substituted-2-(nitromethylene)piperidines and their use for controlling unwanted insects.

One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthes...

The present invention relates to an improved and single step process for producing cyanopiperidine by dehydrating respective piperidine carboxamide employing a suitable dehydrating agent.

Methyl-5-(3-methyl piperidino)pentanamines of general formula ##STR1## in which one of the two radicals R.sup.1, R.sup.2 is hydrogen and the other methyl, are produced by two-stage hydrogenation from 2-methyl glutaronitrile. The compounds are suitable as catalysts in the production of polyurethanes.

A novel 4-cyanopiperidine derivative, which is represented by the following general formula (I): ##STR1## wherein X means a halogen atom, or an acid addition salt thereof, is prepared by reacting N-(2-hydroxyethyl)-4-carbamoylpiperidine or an acid addition salt thereof with a dehydrating and halogenating agent; or by reacting 4-cyanopiperidine or a salt thereof with a compound represented by the following general formula (IV): wherein X has the same meaning as defined above and Y denotes the sam...

3-(.gamma.-aminopropyl)-piperidines can be manufactured by hydrogenating certain bis-cyanoethylated aldimines in the presence of a catalyst and preferably in the presence of an organic solvent. The hydrogenation can be executed at temperatures up to 200.degree.C either without application of pressure or under pressure. Cyclisation occurs with a primary amin being split off. The piperidine derivatives, obtainable according to this invention are suitable as curing agents for epoxy resins.

Ethers and esters of 1-hydroxy-2-(1,1-difluoroalkyl)-1H-imidazo(4,5-b)pyridine compounds, useful as herbicides.

The invention relates to new substituted pyrazol derivatives of general formula (I) in which: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings given in the description, agents with herbicidal action containing at least one compound of formula (I), and their use as herbicides.

The invention relates to new heterocyclylbenzonitriles of the general formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and Het have the meanings given in the description, new processes and new intermediate products for their preparation and their use as herbicides.

A process for making enantiomerically enriched 4-piperidinylglycine having the formula (I), ##STR1## said process comprising (a) combining N-protected glycine ester with 4-piperidone to form didehydroamino acid ester; (b) reducing the didehydroamino acid ester with hydrogen gas in the presence of a rhodium catalyst selected from the group consisting of (R,R)-BPE-Rh; (S,S)-BPE-Rh; (R,R)-DuPHOS-Rh; (S,S)-DuPHOS-Rh; and combinations thereof; whereby a protected compound is formed; and (c) removing ...