This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: ##STR00001## wherein A is a --CH.sub.2--, --O--, --S--, or --S(O)--; and the other substituents are as defined in the specification; or individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents

N-arylsulfonyl-3-aminoalkoxyindoles indole compounds, radioisotopes, stereoisomers, geometric forms, N-oxides, polymorphs and pharmaceutically acceptable salts.

This invention is concerned with novel and pharmaceutically active indole derivatives having the structure: ##SPC1## And the salts thereof with physiologically acceptable acids, in which Each of X and Y is selected from the group consisting of hydrogen, hydroxy, lower alkyl having 1-3 carbon atoms and lower alkoxy having 1-3 carbon atoms, R.sup.1 is selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms and benzyl, R.sup.2 is selected from the group consisting of hyd...

The present invention relates to 2-(1H-indolylsulfanyl)-benzyl amine derivatives of general formula (I): ##STR00001## and pharmaceutical compositions comprising the compounds useful as SSRIs.

Compounds and methods for preparing 2-aryl-3-(aminoaryl)-3-(hydroxyaryl)phthalimidines having a formula of: ##STR00001## wherein R.sup.1 is independently selected from a group consisting of a hydrocarbyl radical, a nitro radical, and a halogen atom; "a" is an integer from 0 4; and Ar.sup.1 and Ar.sup.2 are each independently an aromatic radical, are disclosed. The 2-aryl-3-(aminoaryl)-3-(hydroxyaryl)phthalimidine compounds are useful for preparing other useful monomers and polymers.

This invention relates to novel indolothiopyrones having the formula: ##STR1## wherein R.sub.1 is hydrogen, lower alkyl or aryl; R.sub.2 is hydrogen or halogen; and R.sub.7 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, nitro-substituted-aryl, or .omega.-substituted lower alkyl wherein the substituent is: ##STR2## wherein R.sub.4 and R.sub.5 each represent hydrogen, lower alkyl, or together with the nitrogen atom, form a heterocyclic ring; and R.sub.6 is lower alkoxy or amino, and novel...

A process is described for preparing adrenochrome comprising oxidizing adrenaline or a salt thereof with a persulfate in an aqueous medium at a pH in the range 4 to 8 in the presence of one or more water-soluble salts of bismuth.

A clutch assembly for a motor drive including a motor shaft connected to a flywheel and a brake disc disposed in axially spaced relation to the flywheel. A solenoid armature is axially connected to an output shaft, between the flywheel and brake disc, for selectively and frictionally engaging the flywheel or the brake disc to respectively drive or brake the output shafts.

Compounds of formula (I) or a salt thereof: ##STR1## R.sup.1 is hydrogen, halogen, C.sub.1-6 alkyl, C.sub.3-6 cycloalkyl, COC.sub.1-6 alkyl, C.sub.1-6 alkoxy, hydroxy, hydroxyC.sub.1-6 alkyl, hydroxyC.sub.1-6 alkoxy, C.sub.1-6 alkoxyC.sub.1-6 alkoxy, acyl, nitro, trifluoromethyl, cyano, CHO, SR.sup.9, SOR.sup.9, SO.sub.2 R.sup.9, SO.sub.2 NR.sup.10 R.sup.11, CO.sub.2 R.sup.10, NR.sup.10 SO.sub.2 R.sup.11, CONR.sup.10 R.sup.11, CO.sub.2 NR.sup.10 R.sup.11, CONR.sup.10 (CH.sub.2).sub.p CO.sub.2 R....

This invention relates to substituted indolobenzoxazepines which act as central nervous system depressants and as such are useful as tranquillizers.