Method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors and an assay to screen molecules that are active on these membrane receptors.

Method of producing a recombinant membrane receptor protein by introducing a baculovirus expression vector encoding the membrane receptor protein into a host cell, culturing the resultant host cell for a sufficient time to permit expression of the membrane receptor protein and baculovirus viral particles and separating the cells from the viral particles. The baculovirus viral particles are then recovered.

The present invention describes a method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors and an assay to screen molecules that are active on these membrane receptors.

The invention relates to novel aldolase-inhibiting compounds that can be advantageously used as medicaments (in therapeutic doses), especially for treating certain cancers, due to the inhibition efficacy thereof. An inventive compound corresponds to general formula (I) wherein the aldehyde group (--CHO) and the phenol group (--OH) are linked to two carbon atoms adjacent to the same aromatic chain, i.e., the first aromatic chain, and R is a phosphate group or a phosphate group mimetic linked to a...

An apparatus for insulating against conductive, convective, and radiant heat transmission comprises a plurality of mutually parallel sheets. The sheets may be attached to a retracting device from which they can be drawn to extend in mutually parallel relation and cover a building opening such as a window or onto which they can be retracted to uncover the opening. A number of spacers which may be in the form of collapsible or nestable devices are mounted within the apparatus to separate each pair...

The present invention concerns ergostadientriols which may be recovered from either the fungus R. oligosporus or the fungus R. oryzae as well as from soybeans which have been fermented with either of these fungi. Alternatively, the sterols may be chemically synthesized. The sterols of this invention are antioxidants which may be used in antioxidant compositions alone or preferably with one or more isoflavone. Of particular significance is the discovery that the ergostadientriols of this inventio...

Antioxidants and antioxidant compositions useful as stabilizers for food compositions, including edible fats and oils, and other compositions have been prepared and recovered from a natural source, tempeh, a fermented soybean product. An ergostadientriol which possesses antioxidative properties and which in combination with mixtures of isoflavones provides compositions having exceptional antioxidative properties has been produced.

An electronic calorie counter is disclosed which provides a digital readout of the rate of caloric consumption with exercise by the user by sensing the vertical component of the motion of the user, and translating that motion into electronic impulses. The vertical component of the user's motion is constantly detected using a magneto-electric transducer in combination with means for defining an opto-electric axis in the transducer. The output of the opto-electric means is combined with a clock-co...

Antioxidants and antioxidant compositions useful as stabilizers for food compositions, including edible fats and oils, and other compositions have been prepared and recovered from a natural source, tempeh, a fermented soybean product. An ergostadientriol which possesses antioxidative properties and which in combination with mixtures of isoflavones provides compositions having exceptional antioxidative properties has been produced. This new sterol, either alone or in combination with mixtures of ...

A mix design method for determining the gradation of coarse and fine aggregates to be combined to achieve a predetermined percentage of air void volume and voids in mineral aggregates for a given quantity of asphalt cement. The method uses a volumetric value known as the Riguez Index which is derived from a compacted representative sample of fine aggregates to be used in the mixing plant. Volumes of graded aggregate composites are calculated at various gradation values below the bulking point an...