A process for the production of intermediates having a formula IA ##STR00001## that can be used for the synthesis of cephalosporins, such as cefepime of formula V. The intermediates of formula IA are produced by desilyation of a compound of formula II ##STR00002## wherein R4 is a silyl-protecting group, with a protic solvent to obtain a compound of formula III, ##STR00003## and reacting the compound of formula III with an organic base of formula IV ##STR00004## wherein R2 and R3 together represe...

An apparatus and method for sharing a functional unit. In one embodiment, a processor may include instruction fetch logic configured to issue instructions, and a first functional unit configured to execute instructions issued from the instruction fetch logic and to execute operations issued from a second functional unit, where the operations are issued asynchronously with respect to the instructions. The second functional unit may be configured to provide one or more operands corresponding to a ...

A 3-(Z)-propenyl cephem compound is selectively prepared by reacting a phosphoranylidene cephem compound with acetaldehyde in the presence of a base in a solvent mixture comprising diethyl ether, formula (I), wherein R is a carboxyl protecting group; R.sup.1 is hydrogen or R.sup.2CH.sub.2CO--; and R.sup.2 is ethyl, 2-thiophenyl, phenyl, p-hydroxyphenyl or phenoxy ##STR00001##

The toothpaste dispensing system includes a toothpaste tube and a pair of mating hook and loop fastening strips affixed to opposing surfaces of the toothpaste tube. When the bottom end of the tube is rolled up to dispense toothpaste, the mating hook and loop strips from opposing tube surfaces interlock. Consequently, the emptied, folded portions of the tube are held together, facilitating efficient dispensing of the toothpaste. The hook and loop strips may be permanently affixed to the toothpast...

The object of this invention is to provide a delaminated bottle, which has a base cup fitted tightly around the bottom cylinder of the container and in which a slit is opened easily for the introduction of outside air into the interspace between the outer layer and the inner layer.The container has a male screw on the outer wall of container bottom cylinder and the base cup has a female screw, which is disposed in the upper portion of the inner surface of cylindrical cup wall and is screwed on t...

The appliance has a container that is formed of folded sheet material which bounds an internal chamber and includes a plurality of walls. The container is deformable between a first condition in which the volume of the internal chamber is at a minimum and a second condition in which the volume of the chamber is at a maximum. The container is capable of aspirating a medium when deformed from the first towards the second condition and of expelling a medium when deformed from the second toward the ...

There is provided a solid-state image sensor including a photodetector array in which a plurality of photodetectors are one- or two-dimensionally arranged, each one of the photodetctors including an electrode in a photoelectric conversion region, and transmitting signals when detecting a light passing through the electrode, the solid-state image sensor converting the signals into time sequence electric signals, the electrode being composed of titanium dioxide (TiO.sub.2). The titanium dioxide pr...

1. A process for preparing a 3-alkenylcephem compound or 3-norcephem compound of the formula (3) characterized in that an alkenyl halide of the formula (2), a nickel catalyst, a metal up to -0.3 (V/SCE) in standard oxidation reduction potential and a compound of a metal having a higher standard oxidation reduction potential than the metal are caused to act on a 3-cephem compound of the formula (1) in a solvent ##STR1## wherein R.sup.1 is a hydrogen atom or the like, R.sup.2 is a hydrogen atom or...

The invention relates to a new process for the depletion of 7-amino-3-[(E)-1-propen-1-yl]-3-cephem-4-carboxylic acid in mixtures of 7-amino-3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid and 7-amino-3-[(E)-1-propen-1-yl]-3-cephem-4-carboxylic acid, by means of the crystalline hydrochloride or a metal or amine salt of 7-amino-3-[(Z/E)-1-propen-1-yl]-3-cephem-4-carboxylic acid or by adsorption chromatography.

An elongate container for drinking water formed from a resilient laterally deformable polymerized resin. The container has a wide mouth neck that has first coarse threads on the exterior thereof that are threadedly and frictionally engaged by second coarse threads on the interior of the combined closure and drinking water dispensing assembly. The assembly has a water dispensing tube projecting outwardly therefrom through which a jet of drinking water is discharged when the container is squeezed ...