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The present invention relates to substantially pure piperidine derivative compounds of the formulae: ##STR1## wherein R.sub.1 is hydrogen or hydroxy; R.sub.2 is hydrogen; or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ; R.sub.3 is --COOH or --COOR.sub.4 ; R.sub.4 has 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, al...
The present invention is directed to esters of (+)-.alpha.-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidine methanol, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT.sub.2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.
The present invention is directed to esters of (+)-.alpha.-(2,3 Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT.sub.2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.
Compounds of the formula III ##STR1## in which R.sub.4 and R.sub.5 are CH.sub.3 amd R.sub.6 is hydrogen, have prolonged spasmolytic and anaesthetic activity.
An aspiration sprayer comprises a disc valve for controlling the degree of aspiration over a very wide range by means of a plurality of passages of different sizes formed in the disc valve and selectively introduced into the flow path of the liquid to be aspirated, the disc valve rotating with a knob and being spring-urged into leakproof relationship with that flow path, the carrier liquid with aspiration material entrained therein emerging from the sprayer in a strong jet-like stream the nature...
Apparatus for applying powdered coating materials includes a channel portion wherein the powder coating material is passed around a conduit which delivers an air jet to the powder material, and where the powder material is ionized, and then forced through an outlet channel. The latter is made of nonconductive material, and includes a non-conductive insert disposed in the channel, with the dielectric constant of the insert being different from the dielectric constant of the material of the remain...
A detergent/water mixing system for a water spray gun includes a gun body having a water inlet, a water outlet, a cylindrical transverse through hole between the water inlet and the water outlet, and a bottom axle hole perpendicularly extended from the transverse through hole, a detergent container detachably attached to the gun body at the bottom side, a nozzle jet mounted in the axle hole on the gun body and controlled to eject water into the detergent container and to guide detergent solution...
The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas ##STR00001## which are useful as antihistamines, antiallergic agents and bronchodilators.
The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas ##STR00001## which are useful as antihistamines, antiallergic agents and bronchodilators.
A thermally regenerative deodorizing filter, which comprises a deodorizing filter comprising a deodorant which is adaptable to a thermal regeneration and a honeycomb base material having a heat conductivity which carries the deodorant, and a heating element for regenerating the deodorizing filter which is integrated in the deodorizing filter, wherein the heating element is controlled to a predetermined temperature during the regeneration.
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