The use of the compound 2-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine-1-oxide represented by the formula ##STR1## as well as pharmaceutically acceptable salts, as topical agents to promote hair growth is disclosed.

Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R.sup.1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.

This invention generally relates to the derivatives of 3.6-disubstituted azabicyclo [3.1.0] hexanes of the following formula [IA]. The compounds of this invention can function as muscarinic receptor antagonists, and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of the compounds of the present invention, pharmaceutical compositions contain...

A series of compounds represented by the structural formulas ##STR00001## ##STR00002## and pharmaceutically acceptable isomers, salts, solvates and polymorphs thereof are disclosed. Also disclosed are pharmaceutical compositions containing said compounds and their use as thrombin receptor antagonists and binders to cannabinoid receptors.

Heterocyclic-substituted tricyclics of the formula ##STR00001## or a pharmaceutically acceptable salt thereof, wherein: the dotted line represents an optional single bond; represents an optional double bond; n is 0 2; Q is cycloalkyl, optionally substituted by R.sup.13 and R.sup.14; R.sup.13 and R.sup.14 are independently selected from (C.sub.1 C.sub.6)alkyl, (C.sub.3 C.sub.8)cycloalkyl, --OH, (C.sub.1 C.sub.6)alkoxy, R.sup.27-aryl(C.sub.1 C.sub.6)alkyl, heteroaryl, heteroarylalkyl, heterocyclyl...

The invention provides compounds of the formula: ##STR00001## wherein (a) is a single or double bond; W is CH, CH.sub.2, CHCH.sub.3, C(CH.sub.3).sub.2, C(CH.sub.2).sub.2 or C(CH.sub.2).sub.3; X is N; and Y is H or F, and salts, hydrates, tautomers, pure enantiomers, and enantiomeric mixtures; and a method of treating schizophrenia comprising administering same.

The invention relates to the use of N-substituted indole-3-glyoxylamides of the general Formula I: ##STR00001## and to pharmaceutical compositions having antitumor action.

A compound represented by the structural formula ##STR00001## and pharmaceutically acceptable salts and solvents thereof is disclosed, wherein: the single-dashed line ##STR00002## between the ring carbons to which R.sup.10 and R.sup.34 are attached represents either a single bond or a double bond; the double-dashed line ##STR00003## between X and the carbon to which Y is attached represents either a single bond or an absent bond; X is --O-- or --NR.sup.6-- when the double-dashed line represents ...

The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.

Therapeutically active compounds of formula (I): ##STR00001## wherein the variables shown in formula (I) are defined in the disclosure; and pharmaceutically acceptable salts and esters thereof. The compounds are potent inhibitors of the Na.sup.+/Ca.sup.2+ exchange mechanism.