A method of treating high-protein oedemas in humans or animals by administering the compound 7 hydroxy-coumarin.

The invention relates to the treatment of schizophrenia and senile macular degeneration by administering any one of the benzo-pyrone group of drugs.

Rodenticidal compositions comprising a rodenticidally effective amount of an isomer of a 3-substituted-4-hydroxycoumarin rodenticide which is capable of existing in more than one stable isomeric form. The isomer, for example, the trans isomer of brodifacoum, is significantly less persistently retained in the tissues of non-rodent mammalian or avian species likely to consume the composition or poisoned rodent carcasses than other isomers of the same 3-substituted-4-hydroxycoumarin. The compositin...

The present invention concerns the use of cloricromene (8-chloro-3(.beta.-diethylaminoethyl)-4-methyl-7-ethoxycarbonylmethoxy coumarin) base and the salts thereof to prepare pharmaceutical compositions with cholesterol-lowering activity.

A composition and a method of using the same wherein said composition comprises a rodenticide and an additive selected from the group consisting of 1. polyoxyalkylated alkyl phenols; 2. sorbitan fatty acids and polyoxyalkylated derivatives thereof; 3. polyoxyalkylated fatty amines; 4. polyoxyalkylated branched or linear alcohols, diols or polyols; 5. polyoxyalkylated branched or linear mercaptans; 6. polyoxyalkylated esters; and 7. polyoxyalkylated amines. The composition may optionally include ...

Alkoxylated phenyl and coumarin derivatives useful in the treatment of viral infections are disclosed. The compounds are particularly useful in the treatment of picornaviruses, and more particularly in the treatment of rhinoviruses.

The invention relates to a drug for treating or preventing intrahepatic cholestasis, which is characterized by containing as active agent at least one compound with the general formula I, ##STR1## where R, R.sub.1 and R.sub.2 are independent of each other and can each .dbd.H, C.sub.1-2 -alkyl or C.sub.1-3 -acyl, R.sub.3.dbd.H or OR.sub.4 and R.sub.4.dbd.H, C.sub.1-2 -alkyl or C.sub.1-4 -acyl, and there is a single or double bond between positions 2 and 3, or a physiologically acceptable salt the...

An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (Ill): ##STR1## which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.

Unsubstituted or substituted 5-iodo-6-amino-1,2-benzopyrones and their metabolites are potent, selective and non-toxic inhibitors and supressants of cancer growth and viral infections in a mammalian host. The compounds are particularly useful for treatment and supression of tumors and viruses associated with AIDS, herpetic episodes and cytomegaloviral infections. The methods of treatment of tumorigenic and viral diseases by 5-iodo-6-amino-1,2-benzopyrones and/or its metabolites are described.

A cryogenic refrigerator including cooling means for H.sub.2 before it is expanded in a throttle valve and flows back to one of two containers which are filled with an alloy of A and B in powder form, in which the ratio A : B can vary from 1 : 3 to 2 : 17, wherein A is Ca or one or more of the rare earths, if desired combined with Th and/or Zr and/or Hf, and wherein B is mainly Ni and/or Co, this alloy having the property of readily absorbing H.sub.2 at low temperature and readily desorbing H.su...