A method is provided for inhibiting the development of colon tumorigenesis in a mammal by administering to the mammal a pharmacologically effective amount of an isothiocyanate selected from the group consisting of sulforaphane and phenethyl isothiocyanate.

A method for treating an atopic disorder in a patient is provided. The method comprises administering to the patient an effective amount of at least one of an antifungal and an antibiotic over a period of time. The method further comprises reducing over the period of time the application of emollients to the patient by at least about 50%, relative to the amount of application of emollients prior to treatment.

The present invention provides a method and composition for controlling the growth of microorganisms in aqueous systems, such as industrial process waters. The method includes the steps of adding a synergistically effective amount of a biocide, 2-bromo-2-nitrostyrene ("BNS"), and an oxidant, peracetic acid, to industrial process waters to control microorganism growth. The composition of the present invention comprises a synergistically effective amount of a biocide, 2-bromo-2-nitrostyrene, and a...

The invention relates to methods of using sodium channel modulators, particularly TTX-R sodium channel modulators and/or activity dependent sodium channel modulators to treat a gastrointestinal tract disorders, particularly inflammatory bowel disorders and irritable bowel syndrome.

Synergistic compositions for inhibiting microbial growth contain synergistic mixtures including 2-(2-bromo-2-nitroethenyl)furan ("BNEF") and a compound selected from the group consisting of beta-nitrostyrene ("NS"), beta-bromo-beta-nitrostyrene ("BNS"), methylchloro/isothiazolone ("IZN"), methylenebisthiocyanate ("MBT"), 2,2-dibromo-3-nitrilopropionamide ("DBNPA"), 2-bromo-2-bromomethyl-glutaronitrile ("BBMGN"), alkyldimethylbenzylammonium chloride ("ADBAC"), and beta-nitrovinyl furan ("NVF"). T...

A microbial inhibiting composition and method is disclosed. The composition comprises an amount, effective for the intended purpose of diiodomethyl-p-tolylsulfone and B-bromo-B-nitrostyrene. The method comprises administering an amount of this combined treatment to the particular water containing system for which treatment is desired.

Use of a compound of formula I ##STR1## wherein R.sub.1 is an optionally substituted straight- or branched carbon chain having 12 to 22 carbon atoms which may be optionally interrupted by an optionally substituted phenylene, and each of R.sub.2, R.sub.3, R.sub.4 and R.sub.5, independently, is H or lower alkyl, in free form or in pharmaceutically acceptable salt form, in the prevention or treatment of chronic rejection in a recipient of organ or tissue allo- or xenotransplant, or of acute rejecti...

This invention is directed to a composition comprising 4-chloro-3,6-dinitrobenzotrifluoride and related compounds and method for using it to treat infections caused by organisms that have microtubules.

Use of a compound of formula (I) wherein R.sub.1 is an optionally substituted straight- or branched carbon chain having 12 to 22 carbon atoms which may be optionally interrupted by an optionally substituted phenylene, and each of R.sub.2, R.sub.3, R.sub.4 and R.sub.5, independently, is H or lower alkyl, in free form or in pharmaceutically acceptable salt form, in the prevention or treatment of chronic rejection in a recipient of organ or tissue allo- or xenotransplant, or of acute rejection in a...

The use of novel compositions for preserving aqueous systems normally subject to spoilage is disclosed. The compositions incorporate an antimicrobial agent into an inert and biodegradable carrier. The resulting compositions are stable, active, non-toxic, non-corrosive, biodegradable, compatible with ecosystems while having a flash point above 200.degree. F. and a pleasant odor.