|
Compounds of the formula ##SPC1## Wherein X is O, S or NH, Y is --CH.sub.2 -- and R is nitro, benzoyloxy, alkoxycarbonyloxy, N-mono-alkylaminocarbonyloxy, N,N-dialkylaminocarbonyloxy or an N-substituted-aminoalkoxy group, having antimicrobial activity, e.g., against Trichomonas vaginalis.
Isocyanides of the formula wherein Z represents oxygen or sulfur; R represents hydrogen, halogen, lower alkyl, lower alkoxy, phenyl-lower alkylene, phenyl-lower alkyloxy, trifluoromethyl, cyano, or dimethylaminosulfonyl; R.sup.1 and R.sup.2 represent hydrogen, halogen, lower alkyl, lower alkoxy, phenyl-lower alkylene, phenyl-lower alkyloxy, trifluoromethyl, cyano, dimethylaminosulfonyl, or isocyanido; and n is 1 or 2, provided that at least one of R.sup.1 and R.sup.2 is hydrogen, and that when R...
An antimicrobial peptide containing at least the following amino acid sequence, or a derivative thereof, an antimicrobial agent containing said antimicrobial peptide or a derivative thereof as active components at a concentration of at least 1 .mu.M, an antimicrobial composition containing said antimicrobial peptide or a derivative thereof, and a method for processing products which uses the antimicrobial agent containing at least said antimicrobial peptide or a derivative thereof: (where, A is ...
An antimicrobial peptide containing an amino acid sequence comprising at least from three to six arbitrary amino acid residues, or a derivative thereof, an antimicrobial agent containing said antimicrobial peptide or a derivative thereof as active components at a concentration of at least 2 .mu.M, an antimicrobial composition containing said antimicrobial peptide or a derivative thereof, and a method for processing products which uses the antimicrobial agent containing at least said antimicrobia...
This invention relates to new antimicrobial, antibiotic and bacteriostatic compositions and to methods for their use. The novel compositions of this invention are comprised of an active ingredient of the formula: ##SPC1## Wherein Each Y is hydrogen; Each A is hydroxy, acyloxy or alkoxy; W is hydrogen, hydroxy, acyloxy, or alkoxy; A and Y when taken together, is oxo (O=); W and Y when taken together, is oxo (O=); each X is hydrogen, hydroxy, acyloxy or alkoxy, at least one X being hydroxy; And th...
An antimicrobial composition comprising as active ingredients dodecyl-di-(aminoethyl)-glycine and chlorohexidine or salts thereof.
The stability of tetracycline is improved by compounding it with 8 - hydroxyquinoline or a chlorinated and/or alkyl derivative thereof. In the compositions, which are particularly suitable for topical application, the tetracycline and the quinoline derivative are shown to behave synergistically against certain micro-organisms.
Dihalonitromethylisoxazoles have been prepared from the corresponding nitronate salts. The compounds are useful as broad spectrum antibacterials, antifungals, antiprotozoals and aquatic biocides.
Antimicrobial compositions comprising as active ingredient at least one compound of the general formula ##STR1## (wherein R.sup.1 and R.sup.5, which may be the same or different each represent a hydrogen or halogen atom and R.sup.2, R.sup.3 and R.sup.4 which may be the same or different, each represent a hydrogen atom or a lower alkyl group) in association with an antimicrobial carrier, excipient or diluent. The compounds of formula I may be prepared by reacting a corresponding dihydrothiazolo 8...
Certain phenylthioalkylamines and amides thereof are antifungal or antibacterial agents, or both, and provide a method of controlling the growth of these microorganisms.
|
|