Certain water-soluble copolymers prepared from divinyl ether and maleic anhydride have been found to suppress virus growth. Administration of said copolymers not only suppresses growth in infected animals but also increases resistance to virus infection in healthy animals by stimulating the production of interferon.

The invention relates to hydroxyethylazolyl derivatives, defined herein by formula (I) and particularly to the use of said derivatives for the treatment of viral infections.

Compounds of formula (I) ##STR1## (wherein A represents a ##STR2## grouping; R.sup.1 represents a hydrogen or halogen (e.g. chlorine or bromine) atom or a hydroxy or amino group, R.sup.2 represents a hydrogen atom or a C.sub.1-4 alkyl (e.g. methyl) group, X represents an oxygen or sulphur group and m and n are each 0 or 1 provided that m+n=1) and physiologically acceptable salts and esters thereof, have been found to have potent antiviral activity particularly against herpes infections.

The disclosure relates to a process for producing an antiviral complex by cultivation of Sirodesmium diversum, to novel components of the complex and to derivatives thereof having antiviral activity, to processes for their manufacture, to pharmaceutical compositions containing the complex, the novel components or their derivatives, and to a method of producing an antiviral effect.

A topical pharmaceutical antiviral composition consisting essentially of an inert pharmaceutical carrier or diluent, a complex-former for bivalent cations, and a 5'-triphosphate of a nucleoside or deoxyribonucleoside.

The present invention is concerned with pharmaceutical compositions of antiviral compounds which can be administered to a mammal, in particular a human, suffering from a viral infection. These compositions comprise particles obtainable by melt-extruding a mixture comprising one or more antiviral compounds and one or more appropriate water-soluble polymers and subsequently milling said melt-extruded mixture.

This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties.

Random sequence oligonucleotides that have antiviral activity are described, along with their use as antiviral agents. In many cases, the oligonucleotides are greater than 40 nucleotides in length. Also described are methods for the prophylaxis or treatment of a viral infection in a human or animal, and a method for the prophylaxis treatment of cancer caused by oncoviruses in a human or animal. The methods typically involve administering to a human or animal in need of such treatment, a pharmaco...

This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.

This invention relates to antitumor and antiviral furanoditerpenoid compositions, a process of producing the compositions and a method for inhibiting tumors and viruses utilizing the compositions. More particularly, the new compositions are antitumor and antiviral furanoterpenoids which are derived from marine organisms, i.e., the marine sponge Spongia sp.