Method for improving the rate of release of physiologically active agents from capsules, and pharmaceutical compositions adapted for filling into capsules, said capsules filled with such compositions having improved rates of release of the physiologically active agent therefrom.

Monitorable drug compositions contain known proportions by weight of a drug e.g. methadone and an isotopic analogue e.g. deuterated methadone. A urine specimen or blood specimen can be tested to reveal whether the proportion of the two constituents in the urine is the same as the proportion in the composition that was prescribed to the patient. A discrepancy will reveal that the patient has supplemented his dosage with drugs obtained from another source.

Newly hatched fowl are inoculated intra-cloacally with an anticoccidial effective amount of sporozoities of eimeria tenella to prevent fowl coccidiosis caused by eimeria tenella.

Drug composition having antirheumatic and analgesic indications containing as active ingredients dextro-propoxyphene and phenyl butazone, and treatment comprising administering as active ingredients dextro-propoxyphene and phenyl butazone.

Compositions and methods useful for the prevention or treatment of a human or animal disorder or for the regulation of the human or animal physiological condition are provided. The compositions used comprise, in admixture, a biologically-effective amount of a drug specific for the disorder or condition and a biocompatible, water-soluble, amphiphilic steroid, other than a natural bile salt, which is capable of increasing drug permeability of the human or animal body surface across which the drug ...

The invention relates to a drug system for the treatment and alleviation of the symptoms of epilepsy; as anticonvulsant agent, and for the prevention or alleviation of brain damage due to strokes. The drug system comprises as active ingredient a compound such as MK-801, phencyclidine or as thienyl-cyclohexyl-piperidine (TCP), which is administered in such a manner that it encounters and binds to the N-methyl-D-aspartate (NMDA) receptor channels. This is in the presence of glutamate or glycine, o...

There is disclosed a method for treating and preventing infections caused by bacteria comprising the administration of effective dosage of 3,3-Bis(p-hydroxyphenyl)-phthalide (phenolthalein). The dosage may be administered orally or topically or by injection.

An antiulcer drug comprising Ikarugamycin as its active ingredient is disclosed.

An ophthalmic corneal drug delivery method using a flexable hydrophilic dressing to supply beneficial medications to the corneal area.

A drug-delivery device for prolongedly delivering drugs to patients according to any predetermined time release profile, e.g., increasing, decreasing, constant, pulsing, sinusoidal, and like patterns of release, is fabricated by applying a drug coating of varying or uniform thickness to a relatively drug-impermeable film soluble in body fluids and thence rolling said coated film about itself in spiral or "jellyroll" fashion. Upon administration to the body, the outermost extremities of the film ...