There is described a novel process for producing hydroquinone derivatives of the formula ##STR1## wherein R is an ether protecting group, and their conversion into d-.alpha.-tocopherol, starting from compounds of the formula ##STR2## wherein R is an ether protecting group and R.sup.1 is hydrogen or an ether protecting group.

The invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.17, R.sup.f, A, X, and Y are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1, methods of using the compounds of formula 1 in the treatment of infections and methods of preparing the compounds of formula 1.

A process for the production of methyl dithiocarbazinate includes the steps of providing a mixture comprising hydrazine, solvent, carbon disulfide and base; adding methyl bromide to the mixture; cooling the reaction mixture; and recovering methyl dithiocarbazinate. The methyl dithiocarbazinate may be recovered by filtering the reaction mixture to yield a solid methyl dithiocarbazinate retentate and a liquid filtrate; acidifying the filterate with a mineral acid; and adding methyl isobutylketone ...

Compounds of the invention include 14-mehtyl epothilone derivatives. More generally, preferred compounds of the invention are those that can be produced by altering the epothilone PKS genes as described herein and optionally by action of epothilone modification enzymes and/or by chemically modifying the resulting epothilones produces when those genes are expressed.

A process is provided for the production of a methyl halide by reacting carbon monoxide, hydrogen, and hydrogen halide over a catalyst to give methyl halide and carbon dioxide. The reaction is carried out under anhydrous conditions by using a ratio of carbon monoxide to hydrogen of 2-2.5:1. The catalyst contains a metal from the group copper and zinc. High conversion and yields are obtained in the process.

The use of various novel oxime ethers are described as fragrance chemicals. These chemicals are suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed.

The invention relates to a process for the preparation of methyl formate by reacting methanol with carbon monoxide at a pressure of from 0.5 to 10 MPa abs. and a temperature of from 50 to 150.degree. C. in the presence of a metal alkoxide as catalyst in a reactor, in which a gas stream is withdrawn from the reactor, entrained methyl formate is removed from this gas stream by condensation, and all or some of the remaining gas stream is returned to the reactor as circulating-gas stream and a mean ...

A cleaning composition containing: (a) from about 1.0 to about 15.0% by weight of an anionic surfactant; (b) from about 3 to about 50% by weight of a C.sub.6 C.sub.14 methyl ester primary solvent; (c) from about 1.0 to about 15.0% by weight of a short-chain cosurfactant; (d) from about 1 to about 25% by weight of a polar solvent having a water solubility of from about 1 to 5 g/100 ml; (e) up to about 10.0% by weight of a nonionic surfactant; (f) from about 0.05 to about 3.0% by weight of a thick...

The present invention relates to N-methyl-substituted benzamidazole derivatives of formula (I): ##STR00001## as defined in the specification; pharmaceutical compositions and methods of use thereof.

The use of various novel oxime ethers are described as fragrance chemicals. These chemicals are suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed.