The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.

The present invention is directed to a process for preparing compounds of the general formula (I). Compounds of the general formula (I) are advantageous precursors for preparing phospholane catalysts, especially bisphospholane catalysts. The invention therefore likewise provides for the use of the substances in question for preparing these catalysts. ##STR00001##

It is an object of the present invention to provide an external preparation having enhanced transdermal penetration of a mast cell degranulation inhibitor. It is also an object of the present invention to provide a method for improving the photostability of a preparation containing a mast cell degranulation inhibitor. The present invention provides an external preparation containing a mast cell degranulation inhibitor and a topical anesthetic. Further, the method for enhancing the photostability...

A preventive or therapeutic agent for asthma, comprising HGF or its salt as an active ingredient.

A method for producing M.sub.nB.sub.12H.sub.12, wherein M is a metal or ammonium cation and n is one or two, by combining a metal borohydride and XBH.sub.3; wherein X is a substituted amine; a substituted phosphine; or tetrahydrofuran.

Process for the ring opening polymerisation of cyclomonoolefins by contacting the cyclomonoolefins with a catalyst comsisting of A. a reaction product of a tungsten or tantalum halide with an acetal and B. an organo compound of a metal of groups Ia to IVa of the Periodic Table The molar ratio of tungsten: metal of groups Ia to IVa being from 1:03 to 1:10 and the molar ratio of tantalum: metal of groups Ia to IVa being from 1:1 to 1:10.

Disclosed are antirheumatic compositions containing therapeutically effective amounts of dimethyl aminophenazone and an alkali metal salt of 1-phenyl-4-n-butyl-3,5-dioxopyrazolidine in aqueous solution. The compositions can also contain effective amounts of Lidocaine and Dexamethasone. The compositions described are prepared by bringing together under agitated flow conditions dimethyl aminophenazone with water which contains an alkali metal salt of 1-phenyl-4-n-butyl-3,5-dioxopyrazolidine as a s...

Tetrahalo-substituted ethylenes, and particularly tetrafluoroethylene, may be prepared by reacting a mixed tetrahalomethane with a metal carbonyl in the presence of an inert solvent. The tetrafluoroethylene which is prepared is useful as a starting material for the preparation of polymeric substances.

Perchlorofluorobenzenes, such as liquid trichlorotrifluorobenzene isomer mixtures, are prepared by heating a mixture of two or more halobenzenes selected from the group consisting of hexachlorobenzene, hexafluorobenzene and perchlorofluorobenzenes in which the number of chlorine or fluorine atoms in the components of the mixture differ by at least two, such as a mixture of dichlorotetrafluorobenzene and tetrachlorodifluorobenzene, at a temperature of at least about 475.degree.C. for a period of ...

Resorcinol is made by hydrogenating dinitrobenzene in an aromatic mono-nuclear hydrocarbon-lower alcohol mixed solvent system in the presence of a nickel catalyst at moderate temperatures and pressures. Meta-phenylenediamine thus produced is hydrolyzed using aqueous sulfuric acid. Meta-phenylenediamine and sulfuric acid, 1.2-2.2 moles per mole of meta-phenylenediamine, are contacted in aqueous solution at a temperature of 180.degree.-250.degree.C. in an environment resistant to attack by the rea...