Novel protein having the following physicochemical properties was purified from the occlusion body of entomopoxvirus: (1) it has a molecular weight of 38,000 on SDS polyacrylamide gel, (2) it has an isoelectric point of 3.8, (3) it is stable in the pH range of 5.5-11.0, (4) it is stable at temperature up to 75.degree. C., and (5) it enhances the infection of nuclear polyhedrosis virus. Since the novel protein of the present invention has an activity to enhance the infection of nuclear polyhedros...

A nucleic acid comprising a nucleotide sequence encoding a lysin, which nucleotide sequence comprises the sequence shown in SEQ ID No. 1 or a variant, homologue or derivative thereof. A novel lysin obtainable from a bacteriophage capable of colonising Clostridium perfringens, and the use thereof as a medicament for the treatment of a disorder associated with pathogenic Clostridium bacteria, for example.

This invention relates to polynucleotides, polypeptides encoded by these polynucleotides, to the production of such polynucleotides and polypeptides, and to the uses of such polynucleotides and polypeptides. More specifically, the invention relates to the phosphomevalonate kinase (PMK) gene (ERG8 gene) from Candida Albicans (C. albicans), to methods for its expression yielding phosphomevalonate kinase protein, to hybrid organisms for use in such expression methods, to methods for purification of...

This invention relates to a novel protein capable of inducing an immune response protective against human malarial infection caused by Plasmodium falciparum, and to the cloning and expression of a gene encoding the said protein. The invention further relates to novel vaccines comprising the said protein and to their use in the vaccination of humans at risk from malaria.

A method is disclosed for producing a bland textured protein product. A protein concentrate or isolate is texturized between a pair of heated surfaces which exert a compressive force on the protein material. The protein material is expanded upon release of the compressive force.

Egg yolk protein is acylated with the internal anhydride of a dicarboxylic acid to give an N-carboxyacylated egg yolk protein useful in preparing aqueous oil emulsions, such as salad dressings and mayonnaise, that are sterilizable by heat without coagulation.

A hybrid protein including protein fragments joined together by peptide bonds, the hybrid protein including, in sequential order, beginning at the amino terminal end of the hybrid protein, (a) the enzymatically active Fragment A of diphtheria (b) a fragment including the cleavage domain 1.sub.1 adjacent the Fragment A of diphtheria toxin, (c) a fragment including at least a portion of the hydrophobic domain of Fragment B of diphtheria toxin and not including the generalized eukaryotic binding si...

An improved process is described for recovering proteins from insoluble inclusion bodies produced in transformant microorganisms. Sidestream precipitates isolated from chromatography effluent are resolubilized in a denaturing agent and the resolubilized proteins are renatured either by direct dialysis into denaturant-free buffer or by dialysis into a weaker denaturing agent followed by dialysis into denaturant-free buffer.

An aqueous dispersion containing both acidic and basic proteins and gives better foaming, gelling and emulsion properties than solutions of acidic proteins alone. The basic protein may be made by modifying an acidic protein. Improved aerated products such as meringues and nougat may be made using the solutions.

Novel Protein A-producing Gram-positive bacterial strains and methods for their preparation are disclosed. Also disclosed are methods for producing Protein A using the novel Gram-positive strains.