
The specification discloses that synergistic compositions for depigmentation by topical application have been found which comprise a mixture of hydroquinone, retinoic acid and a corticosteroid formulated in a pharmaceutically-cosmetically acceptable vehicle. An illustrative composition comprising from about 2 percent to about 5 percent hydroquinone, from about 0.05 percent to about 0.1 percent retinoic acid and from about 0.05 percent to about 0.1 percent dexamethasone was particularly effective...











