A nucleic acid to be immobilized and used for hybridization of nucleic acids using an immobilized nucleic acid, which has a polymer comprising a compound having an unsaturated bond, said polymer being bonded to the 3' end or 5' end or both ends of the nucleic acid; a nucleic acid-immobilized substrate comprising a substrate for immobilizing a nucleic acid and the polymer-having nucleic acid immobilized on the substrate; and a method for detecting a nucleic acid by hybridization using an immobili...

Acrylic acid or methacrylic acid is purified by crystallization to obtain crystals and a mother liquor, by a process in which the crystals are washed with a wash liquid containing the acid and having a temperature from 15 to 40.degree. C. Furthermore, a process for the preparation of acrylic acid or methacrylic acid comprises the abovementioned purification process.

Two-component complexes consisting of a polyriboinosinic acid of the formula ##SPC1## Wherein k is an integer from 1 to 3, inclusive; and b is an integer from 1 to 2,000, inclusive; and the metal and ammonium salts thereof, and a polyribo-2-thiocytidylic acid of the formula ##SPC2## Wherein m is an integer from 1 to 3, inclusive; and n is an integer from 1 to 2,000, inclusive; and the metal and ammonium salts thereof, exhibit antimicrobial, in particular antiviral, activity.

Aliphatic, cycloaliphatic, aromatic and heterocyclic carboxylic acid and sulfonic acid chlorides are prepared from the corresponding carboxylic and sulfonic acids and phosgene by reacting the salt-like addition compounds of the said carboxylic or sulfonic acids with N-alkyl-pyrrolidones or N,N-dialkyl-carboxylic acid amides having at least 4 carbon atoms in the molecule in a polar, inert solvent with phosgene at a temperature below 0.degree.C, at atmospheric pressure or elevated pressure, and co...

New copolymers have been prepared from the salts of ethenesulfonic acid and the salts of 2-propene-1-sulfonic acid by solution polymerization methods such as batch or delay. The copolymers have been found useful as dispersants for the clays used in paper coating and in latex stabilization.

Novel penicillins having the formula ##SPC1## Are disclosed along with methods for the preparation of these compounds.

A surgical aid for retaining displaced material in a surgical site in its displaced position. The aid consists of a wire core of aluminum or aluminum alloy or stainless steel and a covering of a suitable elastomer, such as dimethyl polysiloxane polymer, organo-metallically bonded or otherwise contiguous thereto. The aid is malleable, non-toxic and compatible with cell metabolism. It can be clamped to a retractor frame fixed relative to a surgical site and has major advantages over the use of spo...

An instrumentthat determines the HF and the HNO.sub.3 concentration or other mixed acids or single acid of an acid bath measures the potential difference between a fluoride ion selective electrode and a reference electrode and the potential difference between a hydrogen ion selective electrode and the reference electrode. The electrode voltages are applied to a control circuit including a microprocessing unit for calculating and displaying the acid concentrations of the bath and for compensating...

A pump for liquids made up of a tube having an inlet and an oulet with a shaft extending through it. The lower end of the shaft has an impeller and a motor drives the upper end of the shaft. A seal is supported on the shaft between the outlet and the motor preventing liquid from moving up past the seal. The seal fits tightly in the tube and has an inwardly-extending flange with an axially-extending flange with a central bore which receives the shaft. The bore in the axially-extending flange is s...

Certain mono- and disubstituted-5-sulfamylbenzoic acids, many of which are novel, and their use in lowering blood lipid levels in mammals.