Novel hydroxamic acid containing amino acid derivatives are provided that are useful for treatment of inflammation, inflammatory and immunological diseases; lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels; and for treatment or prophylaxis of metabolic disorders.

A process for preparing lipids which contain docosahexaenoic acid (DHA) and/or docosapentaenoic acid (DPA) is disclosed. The process includes the steps of cultivating in a medium a microorganism which belongs to the genus Ulkenia having the ability to produce DHA and/or DPA and recovering the lipids from the culture. The process may further include the step of separating DHA and/or DPA from the lipids.

The present invention relates to a catalyst composition consisting of oxide complexes of vanadium, molybdenum and copper plus an additional metal oxide selected from the group consisting of antimony and germanium or mixtures thereof. These catalysts are especially useful for producing acrylic acid from acrolein and for producing methacrylic acid from methacrolein.

In a step of polymerizing polyamic acid by mixing tetracarboxylic acid dianhydride and diamine and polycondensating the tetracarboxylic acid dianhydride and diamine under the presence of a polymerization-use solvent, a tetracarboxylic acid dianhydride slurry in which a tetracarboxylic acid dianhydride is dispersed in a dispersion medium is used. According to this, it is possible to directly manufacture a polyamic acid solution having a high concentration of polyamic acid more than or equal to 10...

Processes for the preparation of R-lipoic acid or S-lipoic acid comprising a process step selected from a) distillation of dihydrolipoic acid, b) reaction of ##STR1## or its stereoisomer, where Ms is SO.sub.2 --R' and R and R' independently of one another is [sic] C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.3 -C.sub.8 -cycloalkylalkyl, aryl or aralkyl, with sodium sulfide and sulfur in ethanol and reaction with a complex hydride, (c) the extraction of a protic solution of R-dihy...

Impure wet-process phosphoric acid is treated with urea by known processes to produce relatively pure urea phosphate which is then treated with oxalic acid to give solid urea oxalate and purified phosphoric acid product. The urea oxalate is either treated with ammonia to give urea and ammonium oxalate or it is pyrolyzed to produce urea and oxamide.

A process for producing monochloroacetic acid from hydroxyacetic acid which comprises feeding hydroxyacetic acid and aqueous hydrogen chloride to a reaction zone and contacting the hydroxyacetic acid with the aqueous hydrogen chloride in the presence of hydrogen iodide catalyst at a temperature between 100.degree. and 250.degree. C. and a pressure sufficient to maintain the aqueous hydrogen chloride in liquid phase. Preferably the reaction is carried out at a temperature between about 130.degree...

Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen compounds or derivatives thereof attached to a thiol containing species and nucleic acids fluorescently labeled with these reaction products are also provided.

A process for purifying phosphoric acid includes removing volatile components from phosphoric acid rich in impurities to form a crude phosphoric acid liquid substantially free of volatile components; heating the crude phosphoric acid liquid to a temperature above 250.degree. C. in order to decompose phosphoric acid in the crude phosphoric acid liquid and generate gaseous phosphoric anhydride; and introducing the gaseous phosphoric anhydride into water or a dilute phosphoric acid aqueous solution...

The present invention relates to a process for the preparation of R- and S-lipoic acid and R- and S-dihydrolipoic acid comprising(a) reaction of ##STR00001## where MS is SO.sub.2--R' and R and R' independently of one another are C.sub.1 C.sub.6-alkyl, C.sub.3 C.sub.8-cycloalkyl, C.sub.3 C.sub.8-cycloalkylalkyl, aryl or aralkyl, with sodium sulfide and sulfur in methanol. The invention especially relates to processes for preparing pure R- or S-dihydrolipoic acid, which is either used directly or ...