Certain mono- and disubstituted-5-sulfamylbenzoic acids, many of which are novel, and their use in lowering blood lipid levels in mammals.

Novel p-cycloalkylphenylacetic acids which are substituted in .alpha.-position by a carbamylthio, loweralkylcarbamylthio, or diloweralkylcarbamylthio group, and their salts have been prepared. They possess useful antiinflammatory, analgesic, and antipyretic properties.

The present invention relates generally to substituted biphenyloxy acids (such as 4'-aryl-amido-biphenyl-4(3)-yloxy-acids and 4'-aryl-amidomethyl-biphenyl-4(3)-yloxy-acids) and methods of using them, for example, as PAI-1 inhibitors.

The present invention relates to a process for the preparation of crosslinked polymers and copolymers of acrylic acid and methacrylic acid of formula ##STR1## wherein R.sub.1 is hydrogen or methyl. Said process, using ethyl formate as solvent, allows to obtain polymers having low residue of monomer and of solvent and with higher thickening capacity.

The present invention is directed to 2-hydroxy-4-alkylidenecyclohexanealkanoic acids having a mercaptoalkanoic acid substituent at the 3-position. Esters and amides corresponding to the acids referred to above are also encompassed by the present invention. These compounds are useful in the treatment of bronchial asthma and they are obtained by the reaction of an appropriate 2,3-epoxy-4-alkylidenecyclohexanealkanoate with a mercapto alkanoic acid ester in the presence of a tertiary amine. The ind...

Arylcarbonylphenoxyalkylcarboxylic acids, and alkyl esters and salts thereof, are described. The compounds may be formulated into therapeutic compositions and administered to animals, including humans, for the treatment of hyperlipidaemia and related diseases.

Tricarboxylic acids are prepared by reacting unsaturated mono- and dicarboxylic acids of specific carbon atom content in the presence of a catalytic proportion of an unactivated clay and water. The product acids of 34, 35, 36, 38, or 40 carbon atoms are useful as corrosion inhibitors, epoxy resins curing agents, lubricants, polymeric resin plasticizers and intermediates for synthetic polymeric resins.

New compounds have the formula I: ##STR1## wherein R is a C.sub.1 -C.sub.12 straight or branched chain alkyl residue, a C.sub.2 -C.sub.12 straight or branched chain alkenyl residue, a C.sub.5 -C.sub.12 cycloalkyl residue, a C.sub.6 -C.sub.10 aryl residue or a C.sub.7 -C.sub.12 aralkyl residue; and X is a C.sub.1 -C.sub.10 straight or branched alkylene residue, a C.sub.2 -C.sub.10 straight or branched chain alkenylene residue or a C.sub.6 -C.sub.10 arylene residue; as well as derivatives of the c...

Unsaturated organic compounds, in particular .alpha.-acids and .beta.-acids, are purified prior to hydrogenation by mixing them with an adsorbent capable of adsorbing catalyst poisons, preferably activated carbon, and separating the adsorbent containing the catalyst poisons to recover the thus purified unsaturated organic compounds. A significant reduction in the use of hydrogenation catalyst is realized.

A composition and method of making copolymers of salicylic acid and dicarboxylic acid by reacting at least one salicylic acid with at least one dicarboxylic acid and at least one acetic anhydride for every salicylic and dicarboxylic acid present. The composition is useful for functionalizing polyphenylene ethers that are capable of forming copolymers useful for compatibilizing blends of polyphenylene ethers and polyamides.