A method for making multi-layer aspirin tablets including a timed-release layer by coating particles of standard aspirin prior to tabletting with an organic solvent solution containing cellulose acetate phthalate and a plasticizer and pressing together separate layers of the thus-coated aspirin and standard uncoated aspirin into a double-layer tablet.

There is provided a shelf stable solution of aspirin, free of moieties reactive with aspirin, suitable for topical application to the skin compounded from aspirin, N,N-diethyl-m-toluamide USP (DEET), glyceryltriacetate USP (GTA), and acetic anhydride, provided that where GTA is present, at least 20 parts of DEET shall also be present and, after all components shall have been mixed, the resultant solution shall contain an initial amount of between about 1 and about 0.2 parts of acetic anhydride. ...

A mixture of aspirin and powdered milk.

A constant release aspirin tablet comprising from 85-95 weight percent of aspirin, from 1.5-5 weight percent of microcrystalline cellulose, from 1-10 weight percent of cellulose acetate phthalate, from 0.75-4 weight percent of a plasticizer, from 0.75-5 weight percent of corn starch, and from 0.5 to 2 percent of a lubricant.

A sustained release aspirin dosage form permits the continuous delivery of aspirin into the gastrointestinal tract for a period of at least eight hours. The sustained release aspirin dosage form comprises a plurality of polymerically coated aspirin crystals each of which comprises an aspirin seed. The majority of aspirin seeds have a mesh size of from about 30 to about 60 mesh. Each of the aspirin seeds is individually coated with a polymeric mixture, which comprises from about 1.5 to about 15 p...

An analgesic aspirin composition having acetylsalicylic acid and glycine in an amount equal to at least approximately 33.3% of the weight of the acetylsalicylic acid for rendering the aspirin nontoxic.

The reaction rate between aspirin and an equimolar amount of alkaline compound in an aqueous medium is increased by the inclusion of a surface-active agent such as lecithin or an oxyethylene-oxypropylene polymer. As a result the aspirin is completely dissolved within the aqueous medium to increase its availability in the body and reduce damage to gastro-intestinal mucosa, the primary adverse side effect of aspirin.

A stabilized aspirin composition has been found which is comprised of acetylsalicylic acid and dimethyl isosorbide.

A stabilized, essentially sodium free, alkaline and aspirin combination compound which is readily soluble in a preselected fluid, which when dissolved forms potassium acetylsalicylate. Such alkaline and aspirin combination compound consisting essentially of aspirin, having a predetermined particle size. Such aspirin being present in the alkaline and aspirin combination compound generally within a range of between about 325.0 mg and about 1,000.0 mg per unit dose. A preselected alkaline compound ...

Process of producing aspirin-containing capsules which comprises (1) dispersing aspirin particles in a solution of a cellulose derivative in an organic solvent partially miscible with water; (2) adding the dispersion to an encapsulation medium comprising water containing organic solvent(s) partially miscible with water with or without aspirin; (3) stirring the mixture to form a fine dispersion of the aspirin; and (4) evaporating off the organic solvent to deposit the cellulose derivative around ...