In a blood filter of the type having a blood inlet spike which is to be inserted in a blood bag the improvement comprising the outer surface of the blood inlet spike having a roughness of from about 50 to 200 microinches.

A blood sampler comprises a small chamber having a stiletto mounted air-tightly through a flexible top wall with a pointed end of the stiletto positioned inside the chamber opposite an opening in the bottom part of the chamber. The sampler is designed to be mounted in a tool which compresses the chamber by pressing the flexible top wall against the bottom of the chamber. Further, the tool has means for imparting an impact on a blunt outer end of the stiletto to drive the stiletto further through...

A blood pump for circulating blood by a rotor rotating in a space of a casing which is formed substantially in a flat shape and has a suction port and a discharge port, comprises a conical projecting portion provided at the central portion of the rotor, and a blade body formed continuously to a vicinity of the outer periphery of the base portion of the projecting portion, in which upper side recessed passages and lower side passages are alternately and radially formed. Base portions of the upper...

A dynamic blood pump includes a rotating core member and rotating ring portion effective to pre-spin blood before the blood enteres helical pumping channels of the pump. The blood is pumped and further rotated as it moves axially along the helical channels toward a centrifugal section of the pump. At the centrifugal pumping section circumferential velocity differentials are also controlled to diminish damage to the blood. Outwardly of the centrifugal pumping section, a forced-vortex pumping sect...

An improved blood substitute comprises purified hemoglobin, preferably bovine, cross-linked intramolecularly with periodate-oxidized ATP (o-ATP) and intermolecularly with periodate-oxidized adenosine (o-adenosine), combined with reduced glutathione (GSH), and optionally enriched with mannitol, non-electrolytes, and/or electrolytes. The blood substitute has prolonged intravascular persistence, can sustain plasma volume, has low oxygen affinity, can work as a physiological oxygen carrier, has vaso...

A stand alone blood pump which can be used with different types of oxygenators or extra corporeal circuits during surgery. After use the pump is easily detachable from its drive motor to enable a new blood pump to be mounted for the next operation. The pump impeller includes vanes at the base which extend at an angle to the plane of rotation and smoothly merge along a common plane with a plurality of helical fingers respectively. The width of the helical fingers gradually diminishes from the van...

An arterial blood filter device for removing foreign particles and undissolved gases from blood flowing through the device, having a cylindrical housing enclosing a cylindrical filter element between a hollow upper cap forming an inlet chamber and a flat lower cap forming an outlet chamber. The upper cap has a vertical gas outlet and has a horizontal tubular inlet with the outermost wall of the tubular inlet extending tangentially from the outermost wall of the base of the upper cap. A principle...

A blood filter having a bubble separating section includes a generally cylindrical chamber for allowing bubbles to separate from blood, an air discharging vent at an upper end of the chamber, and an inlet conduit horizontally extending from the chamber for introducing blood into the chamber. A blood filter section is disposed below the bubble separating section, including an outlet at a lower end for discharging blood and a filter member disposed between the inlet and the outlet. The axis of the...

The invention relates to stroma-free blood substitutes, which are characterized in that fragments, prepared in a per se known manner, of sulfated glycosaminoglycans are covalently linked with hemoglobin to form products the oxygen binding property of which may be adjusted to be within the range of from 2.66 kPa (20 mmHg) to 10.66 kPa (80 mmHg), and preferably to within the range of from 4.79 kPa (36 mmHg) to 9.33 kPa (70 mmHg) by pre-determining the ratio of hemoglobin to glycosaminoglycan fragm...

A blood substitute suitable for replacing blood in mammalian subjects when performance of surgical procedures at hypothermic temperatures is described. The blood substitute comprises water, electrolytes at physiological concentration, dextran 40 at a concentration sufficient for the blood substitute to achieve a colloidal suspension having a fluid osmotic pressure essentially equivalent to mammalian plasma, HEPES buffer at a physiological pH, dextrose, magnesium ion at a concentration of about 0...