Novel vaccine compositions are provided comprising a hepatitis B antigen formulated with aluminium phosphate. The vaccine compositions may additionally contain an inactivated hepatitis A virus, aluminium hydroxide and formol. The combined hepatitis A and B vaccine formulations can, if desired, be administered to human subjects in a 2 dose regimen. Suitable formulations are illustrated.

A skin wash composition intended for topical application to water-wetted skin comprising an .alpha.-hydroxy acid active ingredient formulated in a mild and non-irritant detergent base consisting of a mixture of a non-ionic alkypolyglucoside surfactant and an amphoteric surfactant.

The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also...

A skin composition which is at least substantially anhydrous and comprises a) At least one water immiscible emollient oil in sufficient quantity to provide emolliency to skin, b) At least one emulsifying agent capable of forming an emulsion, in situ, on the skin with the above oil when water is added to the said composition, the said emulsifier in such quantities that the oil is substantially removed from the skin, c) A water soluble, at least substantially insoluble in the composition skin exfo...

Novel combined vaccine compositions are provided, comprising a herpes simplex virus (HSV) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, a HCMV antigen, Toxoplasma gondii antigen. The vaccine compositions are formulated with an adjuvant which is a preferential stimulator of TH1 cell response such as 3D-MPL and QS21.

There is provided composition comprising i) a thermoplastic polymer ii) a compound having the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are independently selected from an acyl group or a hydrogen atom, wherein at least one of R.sub.1, R.sub.2 and R.sub.3 is an acyl group (a short acyl group) having from 2 to 6 carbon atoms, wherein at least one of R.sub.1, R.sub.2 and R.sub.3 is a branched chain acyl group (a long acyl group) consisting of a saturated chain having 10 to 20 carbon ato...

The invention describes a sports drink, which in addition to conventional additives contains viable lactobacilli having a positive effect on human intestinal mucosa. The sports drink preferably also contains micronutrients and proteins. The invention also refers to a tablet for the preparation of such a sports drink, containing viable freeze-dried lactobacilli in combination with micronutrients. In addition to providing liquid and nutrients replacement, the sports drink also relieves the stress ...

There is provided a pharmaceutical composition comprising (i) a compound of the formula ##STR00001## wherein: X is a hydrocarbyl ring having at least 4 atoms in the ring; K is a hydrocarbyl group; Rs is a sulphamate group; (ii) optionally admixed with a pharmaceutically acceptable carrier, diluent, excipient or adjuvant, wherein the compound is present in an amount to provide a dosage of no greater than 200 .mu.g/day.

1. A composition which is at least substantially anhydrous and comprises a. At least one water immiscible emollient oil in sufficient quantity to provide emollience to skin, b. At least one emulsifying agent capable of forming an emulsion, in situ, on the skin with the above oil when water is added to the said composition, the said emulsifier in such quantities that the oil is substantially removed from the skin, c. A physical stabilization of the composition enhancing amount of a component sele...

The present invention provides a composition comprising: i) at least one compound of formula (I): ##STR00001## wherein R.sub.1 and R.sub.2 are independently selected from a group consisting of hydrogen, unsubstituted or substituted C.sub.1-19 hydrocarbyl or a group of formula (II): ##STR00002## wherein Q is a bond or an unsubstituted or substituted hydrocarbyl group; wherein R.sub.3 is selected from a group consisting of hydrogen and unsubstituted or substituted C.sub.1-18 hydrocarbyl; wherein t...