Hydroypyridine analogs, Dihydropyridine analogs, Trihydropyridine analogs, Hydropurine analogs, Dihydropurine analogs, Trihydropurine analogs, N,N,N,'-trimethyl-N'-(2-hydroxy-3-methyl-1,3-propanediamine analogs, 1-methyl-3-[N-(4-iodophenyl)-carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-Brain capilliary barrier. Once inside the brain these co...

This invention provides remedies for bone diseases characterized by comprising organogermanium compounds expressed by the following formula: ##STR1## (wherein R.sub.1, R.sub.2 and R.sub.3 respectively denote a hydrogen atom, a lower alkyl group such as a methyl or ethyl group, or a substituted or non-substituted phenyl group; X denotes a hydroxyl, O-lower alkyl or amino group; and Y denotes an oxygen or sulfur atom) as an effective ingredient. These remedies are effect for the remedy of osteopor...

An apparatus for detecting ophthalmic diseases such as an inflammation in a patient's eye which includes a laser beam focussed at a selected spot in the eye. The light scattered from the eye is photoelectrically detected and converted into an electrical signal which is subsequently used to determine the protein concentration essential to ophthalmic disease detection in the patient's eye. The laser beam is deflected to scan the eye so far as to exceed a detection slit. The electrical signal deriv...

A treatment for senile dementia of the Alzheimer's type comprising administering to the patient a tertiary amine of the formula ##STR1## wherein R.sup.1 is alkyl, alkoxy, alkylthio or dialkylamino hydroxyl, hydrogen, chlorine or fluorine; R.sup.2 is hydrogen, or when R.sup.1 is hydrogen, alkyl, alkoxy, alkylthio, alkylthioamino, hydroxyl, chlorine or fluorine; R.sup.3 is 1 to 2 carbon alkyl; R.sup.4 is 1 to 3 carbon alkyl; R.sup.5 is an optionally branched 3 to 12 carbon alkylene; X is oxygen or...

A vaccine for the immunization of mammals against Lyme borreliosis (Lyme disease) is disclosed which contains an effective amount of inactivated Borrelia burgdorferi spirochetes dispersed in a physiologically-acceptable, non-toxic liquid vehicle.

A method of diagnosing Alzheimer's disease by the determination of the levels of the hormones somatotropin (human growth hormone) and somatomedin-C (IGF-I) after the administration of the L-dopa provocative test. Blood-sera samples are taken every thirty minutes for a two hour period after the administration of L-dopa, and the samples are tested for the levels of these hormones. These levels are then compared against the levels for normal subjects in the age group of between fifty and sixty. If ...

Alzheimer's disease may be treated with galanthamine.

A treatment for inflammatory disorders, such as herpes simplex, eczema, shingles, atopic dermatitis, psoriasis, etc. The treatment includes the topical application of an ointment base containing a small quantity of triacontanol. The triacontanol-ointment preparation is applied directly to the infected skin area as often as is needed.

A self-administerable method of treating periodontal disease by providing a dilute aqueous solution of a non-toxic benzo-c-phenanthridine salt, pumping the solution through an orifice to provide a pulsating jet stream that is capable of penetrating directly into the periodontal pockets associated with periodontal disease, and applying the jet stream to diseased gingival tissue and into the periodontal pockets.

The present invention is based on the discovery that amyotrophic lateral sclerosis (ALS), Parkinson disease and Alzheimer disease are due to lack of a disorder-specific neurotrophic hormone. Diagnosis is accomplished by assaying hormones specific for a particular neuronal network or system: the motor neurotrophic hormones from muscle in the motor neural system are used to diagnose and treat ALS, dopamine neurotrophic hormones from striatum in the nigrostriatal neural system are used to diagnose ...