This invention relates to the use of flurbiprofen and ibuprofen, their pharmaceutically acceptable salts and esters in a method of increasing bone mass and the treatment and prevention of bone mass loss excepting alveolar bone mass loss or increase. More particularly this invention relates to the treatment of osteoporosis by administering flurbiprofen or ibuprofen, their salts or esters.

A process for treating the blood-brain barrier by the systemic administration of flurbiprofen (3-fluoro-4-phenylhydratropic acid) or a salt or ester thereof. Dosage forms are also disclosed.

The present invention is directed to flurbiprofen-containing compositions for topical administration comprising about 0.5 to 10% flurbiprofen; about 10 to 80% of a lower alcohol; about 0 to 25% of a glycol; about 0 to 5% of a gelling agent; an amount of a pH adjusting agent sufficient to adjust the pH of the composition to a range of from about 2 to less than 4.5; and water in an amount sufficient to make up the balance of the composition, and methods for delivering flurbiprofen-containing compo...

A medicament for immediately treating painful, inflammatory and/or febrile acute diseases contains flurbiprofen as a racemate, a mixture of a racemate with its enantiomers, a pseudoracemate (mixtures of equal parts of S- and R-flurbiprofen) or as a mixture of different parts of S- and R-flurbiprofen in the range extending between pure S and pure R-flurbiprofen as active substance in the form of a pharmaceutically applicable nanosol. This medicament satisfies all requirements of an immediate-effe...

This invention relates to a sugar based or sugar alcohol-based suckable lozenge of the non-steroidal antiinflammatory drug flurbiprofen for the treatment of soar throat.

A process for treating Herpes Type I virus by the systemic administration or topical application of flurbiprofen (3-fluoro-4-phenylhydratropic acid) or a salt or ester thereof. Dosage forms are also disclosed.

A process for treating Herpes Type II virus by the systemic administration or topical application of flurbiprofen (3-fluoro-4-phenylhydratropic acid) or a salt or ester thereof. Dosage forms are also disclosed.

Novel treatments are disclosed for increasing circulating coronary blood flow. These treatments are useful for individuals who are expected to otherwise exhibit symptoms of reduced coronary circulation. Such individuals include those having coronary artery disease, angina, particularly unstable angina and Prinzmetal's angina, and coronary vasospasm. In accordance with the disclosed methods, coronary vasodilation is accomplished through the administration of effective amounts of ibuprofen and/or ...

The topical use of certain flurbiprofen amide derivatives and ketorolac amide derivatives to treat ophthalmic angiogenesis-related and inflammatory disorders of the posterior segment of the eye is disclosed.

A method of reducing bone loss and promoting bone regrowth, once loss has occurred, particularly alveolar bone loss associated wtih periodontal disease, and a composition useful in the method. The method comprises applying to buccal membranes a therapeutically effective quantity of at least one S enantiomer, generally an S(+) enantiomer, of a nonsteroidal anti-inflammatory drug, such as S(+) flurbiprofen or S(+) ketoprofen. The composition is a formulation which is a toothpaste or which is a mou...