Fusion reactor (36) based on the cusped geometry concept in which the problem of indefinite tight plasma containment with inherent stability and high compression of the contained plasma in the reaction zone (19) is solved by an electric potential pot (22) surrounding the reaction zone and having an ion source (37) at the upper potential pot edge (38).

Novel expression vectors are provided for expressing a fusion glycoprotein. The fusion glycoprotein contains the N-terminal globular domain of a retroviral env surface protein linked to a selected glycopeptide. Truncation glycoproteins as well as insertion glycoproteins are expressed using the vectors.

A fusion implant for insertion between opposing vertebrae includes a body having an inner surface defining a hollow inner chamber for containing a graft material therein. The body includes a stress transfer mechanism for transferring stress from the vertebrae surrounding the implant to the graft material contained within the implant. A method is provided for implanting the fusion implant between opposing vertebrae by the steps of inserting an implant into a collapsed disc space between adjacent ...

Novel expression vectors are provided for expressing a fusion glycoprotein. The fusion glycoprotein contains the N-terminal globular domain of a retroviral env surface protein linked to a selected glycopeptide. Truncation glycoproteins as well as insertion glycoproteins are expressed using the vectors.

A DNA sequence encoding a fusion protein comprising influenza virus HA, at a site of which normally occupied by a natural antigenic epitope thereof a different antigenic epitope is provided, is incorporated in a vector which is capable of expressing the fusion protein when provided in a eucaryotic host. When in the form of a viral vector such as a recombinant vaccinia virus, the vector can be used as a vaccine. Alternatively, the fusion protein expressed by the host can be recovered and provided...

Fusion polypeptides and salts thereof comprising at least one IgE-binding domain fused to at least one human serum albumin component, optionally via a peptide linker, and in particular, dimeric fusion polypeptides comprising HSA protein fused, at each of its amino and carboxy termini, to an extracellular domain of the .alpha.-chain of the human high affinity receptor for IgE (Fc.epsilon.RI.alpha.); process for the preparation thereof, functionally equivalent polypeptides which are intermediates ...

A fusion implant for insertion between opposing vertabrae includes a body having an inner surface defining a hollow inner chamber for containing a graft material therein. The body includes a stress transfer mechanism for transferring stress from the vertabrae surrounding the implant to the graft material contained within the implant. A method is provided for implanting the fusion implant between opposing vertabraes by the steps of inserting an implant into a collapsed disc space between adjacent...

A fusion protein suitable for use as a vaccine comprises an amino acid sequence having biological activity which is fused via an intervening hinge comprising from two to eight glycine-proline repeats to the C-terminus of sufficient of the amino acid sequence of a B subunit of an enterotoxin which is capable of ADP-ribosylation of a GTPase.

The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the TolAIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a TolAIII domain or a functional homologue, fragment, or derivative thereof is located towards the N-terminus of the fusion polypeptide and ...

A DNA sequence encoding a fusion protein comprising influenza virus HA, at a site of which normally occupied by a natural antigenic epitope thereof a different antigenic epitope is provided, is incorporated in a vector which is capable of expressing the fusion protein when provided in a eucaryotic host. When in the form of a viral vector such as a recombinant vaccinia virus, the vector can be used as a vaccine. Alternatively, the fusion protein expressed by the host can be recovered and provided...