The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using the aminopeptidase polypeptides and polynucleotides as a target for diagnosis and treatment in aminopeptidase-related disorders. The invention further relates to drug-screening methods using the aminopeptidase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatm...

This invention relates to a novel human deoxyribonuclease, referred to as LS-DNase, that is relatively resistant to inhibition by actin, as compared to human DNase I. The invention provides nucleic acid sequences encoding LS-DNase, thereby enabling the production of LS-DNase by recombinant DNA methods in quantities sufficient for clinical use. The invention also relates to pharmaceutical compositions and therapeutic uses of LS-DNase.

The invention provides a human myotrophin (MYO1) and polynucleotides which identify and encode MYO1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of MYO1.

The present invention provides a human tumor suppressor (HKALL) and polynucleotides which identify and encode HKAL,. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HKALL.

The invention provides a new human lysophospholipase (JHLP) and polynucleotides which identify and encode IHLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating inflammation and disorders associated with expression of IHLP.

Human REQUIEM polypeptides and DNA (RNA) encoding such REQUIEM and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such REQUIEM for the treatment of a susceptibility to viral infection, tumorogenesis and to diseases and defects in the control of embryogenesis and tissue homeostasis, and the nucleic acid sequences described above may be employed in an assay for ascertaining such susceptibility. Antagonists against such R...

The invention provides human keratins (KERT) and polynucleotides which identify and encode KERT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KERT.

Method of controlling human appetite by ingestion of milligram amounts of xanthan gum with water, approximately one-half hour before normal mealtimes.

In human habitations suitable for mass production, there is a need for a flexible foldable film or sheet material having a combination of extreme light resistance, fatigue resistance, and heat reflection. I have found that a superior combination, and the only one for which an accelerated test indicates permanence over a period exceeding 40 years, comprises the following elements: a flexible foldable film assembly, the outermost layer of which consists of opaque flakes, preferably of metal, arran...

A human body massaging apparatus has an inflexible, body contacting cylindrical roller, rotatably mounted on a left and a right handgrip, so that the apparatus may be rolled over a human body to produce a massaging action. The handgrips are cylindrical in shape and of the same diameter as the body contacting, cylindrical roller, permitting the handgrips and the cylindrical roller to contact the human body simultaneously. Hands are easily slid back and forth between the same size roller and handl...