A microprocessor may include a retire queue and one or more data speculation verification units. The data speculation verification units are each configured to verify data speculation performed on operations. Each data speculation verification unit generates a respective speculation pointer identifying outstanding operations on which data speculation has been verified by that data speculation verification unit. The retire queue is configured to selectively retire operations dependent on the spec...

The invention relates to mutant nuclear hormone receptors that encode mutant nuclear hormone receptors, in which particular amino acid residues are substituted with respect to wild type, so as to be able to detect ligand binding to the mutant receptor by either a change in a physical property of the mutant receptor and/or an transcriptional induction of a nuclear hormone receptor construct. The invention also relates to a nuclear hormone receptor response element denoted by the formula YDRXZ com...

A pair of design elements are suitable for display within the interior of a left and right shoe which make up a pair of children's shoes to aid the child in aligning the shoes for proper fitting onto the correct feet. The individual design elements are themselves complete and, further, are not indicators of proper alignment without their association with a picture story which may comprise a simple declarative sentence such that a mental step is required by the child in order to ascertain that th...

Operation of a pushbutton or key mechanism by the operation of a single pushbutton or key through circuitry which may include fiber optics signals all keys on the keyboard included in the particular chord. The device may be built in or simply attached to the keyboard instrument. The keys are spring, and string or wire operated to return a key to its inoperative position when the next key is pressed down.

Operation of a pushbutton or key mechanism by the operation of a single pushbutton or key through circuitry which may include fiber optics signals all keys on the keyboard included in the particular chord. The device may be built in or simply attached to the keyboard instrument. The keys are spring, and string or wire operated to return a key to its inoperative position when the next key is pressed down.

The present invention provides methods that can be used to identify .beta.-amyloid reducing compounds. The present invention is based on the use of organotypic brain slice culturing methods to simultaneously assess the toxicity and .beta.-amyloid reducing activity of a test compound.

A method and apparatus are disclosed for identifying boundaries between thin beds having different resistivities. In one embodiment, the method includes (a) transmitting an oscillatory signal from a first transmitter; (b) determining a first phase difference between signals induced in two receivers by the oscillatory signal from the first transmitter; (c) transmitting an oscillatory signal from a second transmitter; (d) determining a second phase difference between signals induced in the two rec...

An apparatus to identify a replacement of a developing machine comprises a fuse which is disposed at a desired position of the developing machine; a switching part which is disposed at a desired position of a printer body corresponding to the fuse and applies a level of current to the fuse according to a control signal so as to disconnect the fuse; a control unit which outputs a control signal to the switching part so as to check whether the fuse is disconnected when a warming-up operation of a ...

This invention relates to methods to identify specific inhibitors of the purine nucleotide synthesis enzyme, IMP dehydrogenase (IMPDH). IMPDH is an essential enzyme found in all free-living organisms from humans to bacteria and is an important therapeutic target. The invention allows the identification of specific inhibitors of any IMPDH enzyme which can be expressed in a functional form in a recombinant host cell. A variety of eukaryotic or prokaryotic host systems commonly used for the express...

A method and system is provided to uniquely identify a remote method to invoke on a server using a hash value computed from the method signature sent from the client to the server with the call request. When a client wishes to invoke a remote method located on a server, the client sends a hash value identifying the remote method to the server in the "remote method invocation" (RMI) call. In one implementation, this hash value is created by applying a hash function to the method string name and t...