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A number of terpenoid compounds and their epoxides were synthesized and found to prevent insect maturation when applied to insects in an immature stage of growth.
Combinations of organic phosphines and organic nitrogen bases help stabilize complexing solutions containing cuprous and silver salts whose anionic components are Lewis acids, said salts being dissolved in aromatic solvents, when the solutions are in the presence of olefins, to prevent side reactions from occurring during olefin complexing processes in which the above complexing solutions are employed.
New substances named "substance S-PI" and "substance Me S-PI" are concerned which are effective as pepsin inhibitor, the latter substance being methyl ester of the former. The substance S-PI is prepared by fermentation of a new strain of microorganism which has been isolated from soil by the present inventors and named the Streptomyces naniwaensis (EF 44-201), whereas the substance Me S-PI is prepared by methyl esterfying the former substance. A specimen of the Streptomyces naniwaensis (EF 44-20...
Wood is treated in inhibit the iron staining of the wood during shipment in commerce by applying to the wood prior to shipment finely divided insoluble salt of a Group II Metal (beryllium, magnesium, calcium, strontium, barium,, zinc, cadmium and mercury). The preferred anti-stain compounds are the insoluble salts of calcium, zinc and magnesium, particularly zinc oxide and calcium carbonate.
A number of terpenoid compounds and their epoxides were synthesized and found to prevent insect maturation when applied to insects in an immature stage of growth.
This invention relates to novel compounds which are ACAT inhibitors rendering them useful in lowering blood cholesterol levels. The compounds contain two urea or thiourea, amide, or amine moieties or combinations of said moieties and have the following general formula: ##STR1## wherein m and n are zero or one, W and YNH and ##STR2## form the urea, thiourea, amide or amine moieties; and R.sub.1 and R .sub.2 are hydrogen or a hydrocarbon radical.
Compounds having an optionally-substituted purine derivative portion and a carbobicyclic or heterobicyclic portion, which compounds are useful as phosphodiesterase inhibitors, are disclosed. Also disclosed are intermediates, methods for making the inhibitors, pharmaceutical compositions and methods for treating hypertension using the compounds.
Renin inhibiting compounds containing a single .alpha.-amino acid of the formula: ##STR1## and analogs thereof which inhibit the substrate-cleaving acting or renin, pharmaceutical compositions containing these compounds, processes for producing the compounds and methods of treating hypertension which employ the novel renin inhibitors.
A compound of the formula: ##STR1## wherein A is ##STR2## in which X is .dbd.CH-- or .dbd.N--; R.sup.2 is hydrogen, alkyl, phenyl, benzyl or phenethyl; Y is --CH.sub.2--, --NH-- or --O--; and Z is --H.sub.2 or .dbd.O; B is His, Leu, Ile, Nva, Nle, Ala or Val; and R.sup.1 is hydrogen, alkyl, phenyl or phenylalkyl; or a pharmaceutically acceptable salt thereof are renin inhibitors.
The synthesis of the novel fucosidase inhibitors, .beta.-L-homofuconojirimycin and related 1-.beta.-C-substituted deoxymannojirimycins, is disclosed.
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