A class of sulforhodamine labeling reagents capable of binding with a biomolecular species to produce a conjugate with fluorescent properties. The sulforhodamine labeling reagents have the structure: ##STR1## The group X is selected from an alkyl, an olefin, a monocyclic aliphatic saturated hydrocarbon, an aryl, or nothing at all. The group Y is selected from an amide, a substituted amide, or nothing at all. The group Z is selected from a monocyclic aliphatic hydrocarbon, an aryl, or an alkyl, a...

A drum continuously rotating on a vertical axis carries at least two pairs of label transfer members spaced circumferentially around its axis and rotatably connected to the drum on vertical axes. One of the transfer members in each pair is a pick-up member and the other a delivery member, with the pick-up members alternating with the delivery members. The pick-up members are continuously rotated on their axes in one direction while the delivery members are rotated in the opposite direction at th...

Compounds of the formula ##STR1## wherein R.sub.1 is lower alkyl or phenyl lower alkyl: R.sub.2 is phenyl or substituted phenyl; and R.sub.3 is substituted or unsubstituted phenyl, naphthyl or indolyl; Are fluorogenic reagents which react with primary amino groups to form fluorophors. The above compounds are useful for fluorescent labeling of materials of biological importance.

A method for coordinating the rate of processing of a container at a processing station with the rate of feed of said container to and removal from said processing station, comprising selecting a predetermined rate for said processing and said feed and removal, independently and continuously comparing the actual processing rate with said selected rate, independently and continuously comparing the actual feed and removal rate with said selected rate, and independently adjusting the actual rate of...

A labeling station of a labeling machine for bottles or the like having a gripping cylinder rotatable in one direction. The station includes a rotatable carrier and at least one glue segment mounted on the carrier for oscillatory rotational movement about an axis of rotation disposed between the center of curvature of its cylindrically curved pickup surface and the pick up surface, to dispose the center of the pickup surface tangential to the gripping cylinder at the center of the oscillatory mo...

A labeling station in a machine of the type for labeling objects and having a plurality of successively disposed stations, comprising a gluing station a label magazine station and a label transfer station. The labeling station comprises at least one pickup element for labels rotatably mounted on a revolving carrier between the pickup surface thereof and the center of curvature thereof and which is driven so that upon moving past the stations on each revolution of the carrier, its receiving surfa...

A labeling system which utilizes composite label construction and related labeling methods are described. The invention contemplates one or more coupon-type labels placed one over the other onto a package. In one context, the composite label of the invention serves as a combination shipping label and packing list label.

In a labeling machine having a labeling station including a support means for revolving the support about its axis successively past a gluing roller, a label pickup station and a label gripping cylinder, at least one gluing segment on the support axis, the gluing segment having a cylindrically curved pickup surface with a radius smaller than the distance between the support axis and the gripping cylinder, the gripper cylinder and each gluing segment being coupled to one another through a nonunif...

A labeling device including a release liner and a label where the release liner is imprinted with variable information prior to being equipped with the usual release material, i.e., silicone coating.

Novel labeling reagents are useful for radiolabeling proteins such as antibodies with radionuclide metals such as .sup.99m Tc, .sup.186 Re, and .sup.188 Re. The reagents are of the following formula: ##STR1## wherein: each X is independently chosen from O, S, NH, or NR.sub.2, wherein R.sub.2 is a protecting group or an electron withdrawing group; R.sub.1 represents a protecting group, wherein each R.sub.1 is a separate protecting group or the two R.sub.1 symbols are taken together to represent a...