A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.

Compounds or their salts having general formula: A-B--C--NO.sub.2 wherein: A is a drug radical; B is a linker; and C is a bivalent radical.

A pharmaceutical composition comprises an angiotensin II receptor antagonist selected from among compounds having the following formula (I), a pharmacologically acceptable salt thereof, a pharmacologically acceptable ester thereof and a pharmacologically acceptable salt of such ester, and one or more diuretics: ##STR1## The pharmaceutical composition of the present invention has an excellent hypotensive effect and low toxicity, and therefore is useful as a medicament for preventing or treating h...

This invention relates to compounds to formula (1) wherein B is optionally substituted aryl; R.sup.1 and R.sub.2 are the same or different and are independently selected from hydrogen or C.sub.1-3 alkyl; n is 1 or 2, preferably n is 1; m is 0 or 1; R.sup.3 is hydrogen or acyl, R.sup.4 and R.sup.5 are the same or different and are independently selected from amino, alkylamino, dialkylamino, arylamino and C.sub.2 -C.sub.4 cycloalkylamino; X and Y are independently selected from C, H or N provided ...

The present invention concerns analogues of M6P for use in promoting the healing of wounds or fibrotic disorders with reduced scarring, together with methods for doing same.

New crystalline forms of lopinavir are disclosed.

Compounds or their salts of general formula (I): A-B-N(O).sub.s wherein: s is an integer equal to 1 or 2; A=R-T.sub.1-, wherein R is the drug radical and T.sub.1=(CO).sub.t or (X).sub.t', wherein X=O, S, NR.sub.1c, R.sub.1c is H or a linear or branched alkyl or a free valence, t and t' are integers and equal to zero or 1, with the proviso that t=1 when t'=0; t=0 when t'=1; B=-T.sub.B-X.sub.2--O-- wherein T.sub.B=(CO) when t=0, T.sub.B=X when t'=0, X being as above defined; X.sub.2 is equal to R....

The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized contained comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for m...

Compositions have been obtained by extracting rhizomes of Fagopyrum dibotrys with alcohol and concentrating the extract to a powder or syrup, optionally followed by fractionation. The extract is demonstrated to be a potent anti-cancer agent. Its activity at the gene level was analysed.

The present invention concerns an extended release formulation having an accelerating erosion and/or dissolution rate of the surface of the formulation. The formulation comprises a drug having low solubility in water dispersed or dissolved in at least one erasable hydrophilic polymeric matrix.