The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 .beta. hydroxy-16 .alpha., 17-oxido-5 pregnen-20-one, converting the 3 .beta. hydroxy-16.alpha., 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidatio...

A process for preparing fluorochemical monoisocyanates comprises reacting at least one fluorochemical alcohol represented by the formula C.sub.nF.sub.2n+1SO.sub.2NCH.sub.3(CH.sub.2).sub.mOH, wherein n=2 to 5, and m=2 to 4, with 4,4'-diphenylmethane diisocyanate (MDI) in a solvent in which the resulting fluorochemical monoisocyanate is not soluble; wherein the molar ratio of fluorochemical alcohol:MDI is from about 1:1 to about 1:2.5.

A process including reacting a substituted or unsubstituted arylamine or a mixture thereof with a Vilsmeier reagent in the presence of a weakly polar liquid.

A method of preparing shrimps includes boiling them at a pressure exceeding atmospheric pressure, at a temperature exceeding the boiling temperature of water at atmospheric pressure, for keeping the meat of the shrimps in a compressed state while causing the meat to solidify and loosen from the shells of the shrimps. The shrimps are then rapidly cooled for causing the meat to be separated from the shells in an area behind the head of the shrimp and above the tail. Subsequently, the shrimps are p...

This invention provides 9-fluorenylmethoxycarbonyl compounds that are useful as intermediates for preparing glycopeptide antibiotics.

The invention relates to .beta.-alanine amides of general formula (I), wherein: R.sup.1 represents hydrogen or C.sub.1-6 alkyl that is optionally substituted by hydroxy, amino, carboxy, carbamoyl, methylmercapto, guanidino, optionally substituted aryl or heteroaryl, and; R.sup.2 represents hydrogen or R.sup.1 and R.sup.2, together, form a group of formula --(CH.sub.2).sub.n--, wherein n is 3 or 4. Said .beta.-alanine amides are produced without using an amino protective group by reacting the cor...

A smear preparing apparatus for preparing a smear of a specimen on a glass slide by using a spreader based on a smearing condition, the apparatus includes a memory for storing smearing conditions in connection with pertinent information required for establishing the smearing condition; and a controller for retrieving one of the stored smearing conditions corresponding to the pertinent information of the specimen from the memory and for determining it as the smearing condition of the specimen.

The invention relates to a continuous process for preparing caprolactam by Beckmann rearrangement of cyclohexanone oxime, said process comprising a) feeding (i) oleum and (ii) cyclohexanone oxime into a first reaction mixture comprising caprolactam, sulfuric acid and SO.sub.3, b) feeding (iii) a portion of the first reaction mixture and (iv) cyclohexanone oxime into a second reaction mixture comprising caprolactam, sulfuric acid and SO.sub.3, c) withdrawing a portion of the second reaction mixtu...

This invention provides intermediates useful in a method of preparing amine stereoisomers. It also provides a method of preparing sulfoxide and sulfinylamine stereoisomers using certain of the intermediates.

In particular, zolmitriptan or a pharmaceutically acceptable salt thereof, which includes a) Preparation of the diazonium salt of the aniline hydrochloride (II); followed by reduction and acidification to give hydrazine (III); b) In situ Reaction of the hydrazine hydrochloride (III) with .alpha.-keto-.delta.-valerolactone, to give the hydrazone (IV); c) Fischer indole synthesis of the hydrazone (IV), to give the pyranoindolone of formula (V); d) Transesterification of the pyranoindolone (V) to p...