The invention provides a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and represent hydrogen or alkyl of 1-6 carbon atoms, R.sup.3 represents hydrogen, alkyl of 1-6 carbon atoms, or phenyl, X is Na, K, Li, or CSNHR.sup.4 wherein R.sup.4 is hydrogen or alkyl of 1-6 carbon atoms and n is 3, 4 or 5 or a pharmaceutically acceptacle acid addition salt of a compound where X is CSNHR.sup.4. The compounds of formula I wherein X is CSNHR.sup.4 are anti-ulcer agents...

5'-Acetonylvincristine and related compounds including the corresponding 1-desmethyl derivative, useful in inhibiting the growth of experimental tumors.

5'-Hydroxyleurosine, 5'-hydroxyleuoformine and related compounds, useful in inhibiting the growth of experimental tumors.

New proline derivatives and related compounds which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

Acrylamide and related monomers are improved by incorporating therein an effective polymerization inhibitor in an amount greater than that which is inherently present in the monomer and a borane, i.e., sodium borohydride.

3-Amino-2-hydroxy-4-phenylbutanoic acid and esters thereof as well as new derivatives thereof which are related to bestatin in their chemical structure are active to enhance the immune response in living animals.

A composite fiber or filament comprising a core or substrate coated with a cellular foam, and an outer circumference characterized by a substantially continuous, microcellular breathable and abrasion-resistant aspect.

An improved pipette device for removing and transferring a plurality of liquid samples to and from a multi-well tray is disclosed. The pipette device comprises the housing having an elongated plate defining a first chamber therein. A patterned array of collector conduits are joined to the plate such that a first outwardly extending section extends into the chamber and a second outwardly extending section, in flow communication with the first, extends away from the chamber and toward the tray. A ...

This invention relates to the preparation of vincadifformine and related derivatives which are useful as starting material for the synthesis of among other alkaloids vincamine and other similar compounds possessing interesting psychopharmacologic properties. A tetrahydro-.beta.-carboline (II) is reacted with benzoyl chloride to provide a 2-benzoyl-1,2,3,4-tetrahydro-9H-pyrido-(3,4-b)-indole (III). Then compound (III) is reduced to give a 2-benzyl-1,2,3,4-tetrahydro-9H-pyrido-(3,4-b)-indole (IV)....

Peptides of the formula: ##STR1## wherein: X is H, --NH.sub.2, --NH--Gly--Ala, --NH--D--Ala--Ala, --NH--Gly--Gly--Gly, --NH--acetyl, or --NH--benzoyl; X.sub.1 is His or Arg; X.sub.2 is His, Glu, Tyr, Trp, or Phe; X.sub.3 is Trp, D-Trp, or 6-F-D-Trp; and X.sub.4 is a D-.alpha.-amino acid; or the reduced, linear form thereof, or a non-toxic, pharmaceutically acceptable acid addition salt thereof; inhibit the release of growth hormone, insulin, and glucagon; and show prolonged inhibition activity. ...