A compound of the formula (I) or a pharmacologically acceptable salt, ester or other derivative thereof: ##STR1## R.sup.1 is H or NHOH. R.sup.2 is H, optionally substituted alkyl, cycloalkyl or a group --AR.sup.6. A is an alkylene which may be optionally interrupted by O, --S(O)m-- or --N(R.sup.9). R.sup.6 is a group (II), (III), (IV) ##STR2## X is O, S, --N(R.sup.10)--, --C(R.sup.11)(R.sup.12)--. Y is O, CO, --S(O)n--, --N(R.sup.10)--, --C(R.sup.11)(R.sup.12)--. Each of R.sup.7 and R.sup.8 is H...

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders ##STR1##

A sulfonamide derivatives of formula (I) ##STR1## a non-toxic salts, an acid addition salts or a solvates thereof which has an inhibitory effect on elastase.

Certain sulfonamide inner salts, such as 2-[N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]aminosulfonyl]benzoic acid methyl ester, dimethylsulfonium inner salt, possess utility as herbicides.

As-Triazinylaminocarbonylsulfonamide N-oxides are useful as agrichemicals and in particular as herbicides.

A compound, or pharmaceutically acceptable salt thereof, having the formula: ##STR1## wherein X is ##STR2## wherein R is C.sub.3 -C.sub.12 alkyl or aralkyl, branched or unbranched, unsubstituted aryl, haloaryl, or C.sub.3 -C.sub.22 alkenyl, branched or unbranched; wherein R.sub.1 is H, OH or OCH.sub.3, and wherein R.sub.2 is OH or H, at least one of R.sub.1 and R.sub.2 being OH or OCH.sub.3. These sulfonamides have analgesic and anti-irritant activity when administered to humans and lower animal...

Certain sulfonamide inner salts, such as 2-[N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]aminosulfonyl]benzoic acid methyl ester, dimethylsulfonium inner salt, possess utility as herbicides.

Disclosed is 3-chloro-2-pyridine sulfonamide, said compound being useful as an insecticide.

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and co...

Ortho-Sulfonamide benzenesulfonylureas, such as N-cyclopropyl-N'-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-1,2-benzened isulfonamide, are useful as pre-emergent and post-emergent herbicides.