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Novel supports useful in solid phase synthesis of oligonucleotides of the formula ##STR1## wherein .circle.P is a material selected from the group consisting of functionalized glass micropellets, silica functionalized by aminoalkyl trialkoxysilane capable of to obtain for ##STR2## Kieselguhr, polytetrafluoroethylene, cellulose and metallic oxides, m is an integer from 1 to 20, A is selected from the group consisting of alkyl of 1 to 20 carbon atoms, saturated cycloalkyl of 3 to 12 carbon atoms, ...
Anipamil and its salts with physiologically tolerated acids are used for the preparation of drugs having antiarteriosclerotic properties and in the treatment of arteriosclerosis.
This application relates to the use of certain amines of formula (I) ##STR00001## for combatting and preventing systemic and local complement activation, and in particular to the use of meglumine and derivatives and optionally salts thereof in combatting and preventing said activation. The amines are also of use in combatting activation of the kinin/kallikrein system or blood coagulation system.
The present invention relates to use of peptide to which G-protein coupled receptor protein recognizes as a ligand. Since the ligand polypeptide of the present invention has a stimulating action on oxytocin secretion, it is useful as a drug for ameliorating, preserving or treating various diseases related to oxytocin secretion such as uterine inertia, atonic hemorrhage, placental expulsion, subinvolution and the like.
A method of treating iron induced cardiac disease in a patient with iron overload, such as in thalassemia or the like comprising administering to the patient a therapeutically effective amount of deferiprone or a physiologically acceptable salt thereof sufficient to treat iron induced cardiac disease normally associated with iron overload.
The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an antineoplastic agent in the therapeutic treatment of cancer. Specifically, the treatment of lymphoma with 3',4'-anhydrovinblastine is disclosed.
The use of a 2-(C.sub.3-5 -alkyl)-BIT or 2-aralkyl-BIT such as 2-phenylethyl-BIT as a fungicide for plastics materials. 2-n-Butyl-BIT is preferred.
For forming gateside packs, roof supports, stoppings, etc. in a mine from pit dirt with a quick setting cement, shuttering is employed having a main frame with side walls, each side wall having hydraulically operable extension plates to adjust the wall height. The front plate of the shuttering, with its adjustable extension plates, is movable between the side plates in a direction normal to the front plate, hydraulic rams being provided for this purpose. After material has been injected into the...
It is the object of the present invention to provide utensils for table use or cooking use, which can easily improve the taste of food and drink and make them tasty without using particular energy in a short time. The utensils for table use or cooking use according to the present invention have their surface coated with a film of titanium oxide; when they are exposed to sunrays, an electric light or the like, electrons and positive holes are formed on the film of titanium oxide on the surface th...
The invention concerns the use of the quinazoline derivatives of Formula (I) Wherein each of m, R.sub.1, n, R.sub.2 and R.sub.3 have any of the meanings defined in the description in the manufacture of a medicament for use in the prevention or treatment of T cell mediated diseases or medical conditions such as autoimmune diseases like transplant rejection or rheumatoid arthritis in a warm-blooded animal. ##STR00001##
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