We claim a therapeutic method of inducing programmed cell death comprising administering to a recipient a peptide of 10 25 amino acids, comprising the sequence: (KR)xxYxxx(F/Q)L(L/M) wherein x is any amino acid.

The present invention relates to a use indicator apparatus having a power-sensing mechanism and an indicator. The indicator includes a first state and a second state wherein the indicator is maintained in the first state until a required amount of power is applied to the sensing mechanism. Upon reaching the required amount of power, indicator switches from the first state to the second state.

According to the invention there is provided the use of melagatran, or a pharmaceutically acceptable derivative or prodrug thereof, in the manufacture of a medicament for the treatment of inflammation.

The present invention provides the use of impact resistant, stress cracking resistant copolycarbonates with particularly good low temperature properties for applications in which particularly good low temperature properties are required, e.g., for automobile construction or external applications, and new copolycarbonates themselves.

Titanocenes with, for example, .pi.-cyclopentadienyl ligands in which one or two carbo- or heterocyclic aromatic rings are bonded to the titanium, the aromatic rings being substituted by fluorine in at least one of the two ortho-positions relative to the metal-carbon bond and being substituted by at least one free or etherified or esterified polyoxaalkylene radical, are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated substrates.

A composition containing a substituted cyclic anhydride and a hydroxy-oxime. The cyclic anhydride may be a succinic anhydride derivative such as dodecenyl succinic anhydride or a polymer containing cyclic anhydride groups such as polyisobutenyl succinic anhydride. The oxime may be 2-hydroxy-5-nonylbenzaldoxime or 2-hydroxy-5-nonylacetophenone oxime. The composition may be used to inhibit corrosion of metals, particularly iron. The composition may also include further components which are effecti...

A particulate inorganic solid, especially hydrated alumina or magnesium hydroxide, which has been treated with a hydroxybenzene derivative of a defined type, particularly a gallate. The treated solid may be incorporated into a polymer especially a thermoplastic polymer such as polypropylene. Alternatively, the solid, the hydroxybenzene derivative and the polymer can be blended together. The composition obtained can be processed even when containing 70% by weight of the inorganic solid.

A composition comprising a chelating compound which is a macrocyclic compound containing at least two coordinating centers in the ring, at least one of which is a neutral base moiety, and an organic acid containing at least one alkyl or alkenyl group containing 8 or more carbon atoms. The macrocyclic compound contains at least 10 ring atoms and especially at least 12 ring atoms. The neutral base moiety is typically a nitrogen moiety. Preferably there are at least four coordinating centers at lea...

Microcapsules containing at least one leuco dye, at least one photopolymerisation initiator and at least one photopolymerisable monomer corresponding to the following formula wherein A stands for a 3- to 6-valent organic group having the following meanings: a) a saturated hydrocarbon group having 5 to 25 carbon atoms or b) ##STR1## or c) ##STR2## wherein A.sub.1, A.sub.2, R.sub.3, R.sub.4, o and p have the meanings indicated in the description, X denotes O or NR.sub.2, L.sub.1 denotes a divalent...

The present invention relates to the use of sodium channel antagonists in the treatment of diseases mediated by, or exacerbated by, neuronal apoptosis, in particular sensory neuronal apoptosis.